Association between Helicobacter pylori infection and cardiovascular risk factors among patients in the northern part of Afghanistan: A cross-sectional study in Andkhoy City

Mohammad Shoaib Hamrah, Mohammad Hassan Hamrah, Hideki Ishii, Susumu Suzuki, Mohammad Hussain Hamrah, Ahmad Edris Hamrah, Ahmad Elias Dahi, Kyosuke Takeshita, Mohammad Hashem Hamrah, Akbar Fotouhi, Junichi Sakamoto, Toyoaki Murohara

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Background: The association between Helicobacter pylori infection and cardiovascular risk factors remains controversial. The high prevalence of H. pylori infection among Afghan patients warranted the investigation of this association. The aim of the present study was to determine the association between H. pylori infection and cardiovascular risk factors among patients visiting an outpatient clinic in Andkhoy, Afghanistan. Methods: We performed a cross-sectional study of 271 consecutive patients in an outpatient clinic in Andkhoy, Afghanistan from April 2017 to June 2017. The diagnosis of H. pylori infection was achieved using an enzyme-linked immunosorbent assay test. The patients were divided into H. pylori positive (n=189) and H. pylori negative (n=82) groups. The association between H. pylori infection and cardiovascular risk factors was analyzed. Results: Of the total 271 study participants, 102 (37.6%) were male and 169 (62.4%) female. The mean age ± standard deviation of the patients who were H. pylori-positive and H. pylori-negative was 51.0 ± 17.6 years and 51.6 ± 17.6 years, respectively. In multivariate logistic regression analyses, H. pylori infection was significantly associated with diabetes mellitus (DM) (odds ratio [OR] 3.16, 95% confidence interval [CI] 1.31-7.62, P = 0.011), and body mass index (BMI) levels (OR 1.17, 95% CI 108-1.26, P < 0.001). Conclusions: Our study indicated that H. pylori infection was significantly associated with DM and elevated BMI levels in patients from an outpatient clinic in Andkhoy, Afghanistan. More aggressive measures, including DM, obesity control, and H. pylori eradication are needed.

Original languageEnglish
Pages (from-to)1035-1039
Number of pages5
JournalAsian Pacific Journal of Cancer Prevention
Volume19
Issue number4
DOIs
Publication statusPublished - 01-04-2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Cancer Research

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