Association between markers of arterial stiffness and atrial fibrillation in the Circulatory Risk in Communities Study (CIRCS)

CIRCS investigators

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background and aims Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. Methods We conducted a cross-sectional population-based study of 4264 men and women aged 40–79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co., Kyoto, Japan). Atrial fibrillation was estimated by the Minnesota codes using resting electrocardiograph (ECG). Results The prevalence of atrial fibrillation and total arrhythmia were higher with larger AI values. These associations did not change after adjustment for known cardiovascular risk factors. The multivariable odd ratios (95% confidence intervals) in the highest versus lowest tertiles of AI were 3.4 (1.4–8.6, p for trend = 0.008) for atrial fibrillation and 1.8 (1.2–2.7, p for trend = 0.004) for total arrhythmia. There was no association of central or brachial pulse pressure levels with the prevalence of atrial fibrillation or total arrhythmia. Conclusions AI values, but not brachial or central pulse pressures, were positively associated with the prevalence of atrial fibrillation and total arrhythmia, independent of cardiovascular risk factors.

Original languageEnglish
Pages (from-to)244-248
Number of pages5
JournalAtherosclerosis
Volume263
DOIs
Publication statusPublished - 08-2017

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Vascular Stiffness
Atrial Fibrillation
Cardiac Arrhythmias
Blood Pressure
Arm
Population
Arterial Pressure
Japan
Electrocardiography
Odds Ratio
Confidence Intervals
Delivery of Health Care
Equipment and Supplies

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

@article{0a26ac6e6a234c9ca36aae8233144188,
title = "Association between markers of arterial stiffness and atrial fibrillation in the Circulatory Risk in Communities Study (CIRCS)",
abstract = "Background and aims Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. Methods We conducted a cross-sectional population-based study of 4264 men and women aged 40–79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co., Kyoto, Japan). Atrial fibrillation was estimated by the Minnesota codes using resting electrocardiograph (ECG). Results The prevalence of atrial fibrillation and total arrhythmia were higher with larger AI values. These associations did not change after adjustment for known cardiovascular risk factors. The multivariable odd ratios (95{\%} confidence intervals) in the highest versus lowest tertiles of AI were 3.4 (1.4–8.6, p for trend = 0.008) for atrial fibrillation and 1.8 (1.2–2.7, p for trend = 0.004) for total arrhythmia. There was no association of central or brachial pulse pressure levels with the prevalence of atrial fibrillation or total arrhythmia. Conclusions AI values, but not brachial or central pulse pressures, were positively associated with the prevalence of atrial fibrillation and total arrhythmia, independent of cardiovascular risk factors.",
author = "{CIRCS investigators} and Renzhe Cui and Kazumasa Yamagishi and Isao Muraki and Mina Hayama-Terada and Mitsumasa Umesawa and Hironori Imano and Yuanying Li and Eshak, {Ehab S.} and Tetsuya Ohira and Masahiko Kiyama and Takeo Okada and Akihiko Kitamura and Takeshi Tanigawa and Hiroyasu Iso",
year = "2017",
month = "8",
doi = "10.1016/j.atherosclerosis.2017.06.918",
language = "English",
volume = "263",
pages = "244--248",
journal = "Atherosclerosis",
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}

Association between markers of arterial stiffness and atrial fibrillation in the Circulatory Risk in Communities Study (CIRCS). / CIRCS investigators.

In: Atherosclerosis, Vol. 263, 08.2017, p. 244-248.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association between markers of arterial stiffness and atrial fibrillation in the Circulatory Risk in Communities Study (CIRCS)

AU - CIRCS investigators

AU - Cui, Renzhe

AU - Yamagishi, Kazumasa

AU - Muraki, Isao

AU - Hayama-Terada, Mina

AU - Umesawa, Mitsumasa

AU - Imano, Hironori

AU - Li, Yuanying

AU - Eshak, Ehab S.

AU - Ohira, Tetsuya

AU - Kiyama, Masahiko

AU - Okada, Takeo

AU - Kitamura, Akihiko

AU - Tanigawa, Takeshi

AU - Iso, Hiroyasu

PY - 2017/8

Y1 - 2017/8

N2 - Background and aims Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. Methods We conducted a cross-sectional population-based study of 4264 men and women aged 40–79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co., Kyoto, Japan). Atrial fibrillation was estimated by the Minnesota codes using resting electrocardiograph (ECG). Results The prevalence of atrial fibrillation and total arrhythmia were higher with larger AI values. These associations did not change after adjustment for known cardiovascular risk factors. The multivariable odd ratios (95% confidence intervals) in the highest versus lowest tertiles of AI were 3.4 (1.4–8.6, p for trend = 0.008) for atrial fibrillation and 1.8 (1.2–2.7, p for trend = 0.004) for total arrhythmia. There was no association of central or brachial pulse pressure levels with the prevalence of atrial fibrillation or total arrhythmia. Conclusions AI values, but not brachial or central pulse pressures, were positively associated with the prevalence of atrial fibrillation and total arrhythmia, independent of cardiovascular risk factors.

AB - Background and aims Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. Methods We conducted a cross-sectional population-based study of 4264 men and women aged 40–79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co., Kyoto, Japan). Atrial fibrillation was estimated by the Minnesota codes using resting electrocardiograph (ECG). Results The prevalence of atrial fibrillation and total arrhythmia were higher with larger AI values. These associations did not change after adjustment for known cardiovascular risk factors. The multivariable odd ratios (95% confidence intervals) in the highest versus lowest tertiles of AI were 3.4 (1.4–8.6, p for trend = 0.008) for atrial fibrillation and 1.8 (1.2–2.7, p for trend = 0.004) for total arrhythmia. There was no association of central or brachial pulse pressure levels with the prevalence of atrial fibrillation or total arrhythmia. Conclusions AI values, but not brachial or central pulse pressures, were positively associated with the prevalence of atrial fibrillation and total arrhythmia, independent of cardiovascular risk factors.

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U2 - 10.1016/j.atherosclerosis.2017.06.918

DO - 10.1016/j.atherosclerosis.2017.06.918

M3 - Article

C2 - 28683363

AN - SCOPUS:85021634325

VL - 263

SP - 244

EP - 248

JO - Atherosclerosis

JF - Atherosclerosis

SN - 0021-9150

ER -