Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders

R. Hashimoto, T. Suzuki, N. Iwata, Y. Yamanouchi, T. Kitajima, A. Kosuga, M. Tatsumi, N. Ozaki, K. Kamijima, H. Kunugi

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Two research groups have recently reported a significant association between schizophrenia and genetic variants of Frizzled-3 (FZD3) gene. We examined a possible association in a Japanese sample of schizophrenia, bipolar disorder, unipolar depression and controls with four single nucleotide polymorphisms (SNPs), tested in previous reports. We failed to find significant association in the four SNPs or haplotype analysis. The FZD3 gene might not play a role in conferring susceptibility to major psychosis in our sample.

Original languageEnglish
Pages (from-to)303-307
Number of pages5
JournalJournal of Neural Transmission
Issue number2
Publication statusPublished - 02-2005

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry


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