Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid: A case report

Yusuke Matoba; Kouji Banno; Yusuke Kobayashi; Iori Kisu; Daisuke Aoki

doi:10.1016/j.pdpdt.2019.06.019

Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid: A case report

Yusuke Matoba
, Kouji Banno
, Yusuke Kobayashi
, Iori Kisu
, Daisuke Aoki

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Surgical resection for atypical polypoid adenomyoma (APA) is an option for fertility preservation. Due to the high recurrence rate of APA, studies have been conducted to improve total resection of tumors. Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) improves tumor resection, but this has not been applied for APA. The patient was 35-year-old. After initial treatment, the APA lesion did not disappear. We performed hysteroscopic tumor resection using 5-ALA-PDD. Only one PDD-positive lesion was found and histopathologically diagnosed as APA. Other areas were PDD-negative and showed no histopathologic APA or malignant findings. This is the first report of hysteroscopic 5-ALA-PDD for APA. This method makes it easy to identify morbid lesions, and may lead to improved total resection and decreased recurrence.

Original language	English
Pages (from-to)	295-297
Number of pages	3
Journal	Photodiagnosis and Photodynamic Therapy
Volume	27
DOIs	https://doi.org/10.1016/j.pdpdt.2019.06.019
Publication status	Published - 09-2019
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biophysics
Oncology
Dermatology
Pharmacology (medical)

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10.1016/j.pdpdt.2019.06.019

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@article{b9decd1d337d456cbae48cf2ad10987c,

title = "Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid: A case report",

abstract = "Surgical resection for atypical polypoid adenomyoma (APA) is an option for fertility preservation. Due to the high recurrence rate of APA, studies have been conducted to improve total resection of tumors. Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) improves tumor resection, but this has not been applied for APA. The patient was 35-year-old. After initial treatment, the APA lesion did not disappear. We performed hysteroscopic tumor resection using 5-ALA-PDD. Only one PDD-positive lesion was found and histopathologically diagnosed as APA. Other areas were PDD-negative and showed no histopathologic APA or malignant findings. This is the first report of hysteroscopic 5-ALA-PDD for APA. This method makes it easy to identify morbid lesions, and may lead to improved total resection and decreased recurrence.",

keywords = "5-Aminolevulinic acid, Atypical polypoid adenomyoma, Hysteroscopy, Photodynamic diagnosis",

author = "Yusuke Matoba and Kouji Banno and Yusuke Kobayashi and Iori Kisu and Daisuke Aoki",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2019",

month = sep,

doi = "10.1016/j.pdpdt.2019.06.019",

language = "English",

volume = "27",

pages = "295--297",

journal = "Photodiagnosis and Photodynamic Therapy",

issn = "1572-1000",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid

T2 - A case report

AU - Matoba, Yusuke

AU - Banno, Kouji

AU - Kobayashi, Yusuke

AU - Kisu, Iori

AU - Aoki, Daisuke

PY - 2019/9

Y1 - 2019/9

N2 - Surgical resection for atypical polypoid adenomyoma (APA) is an option for fertility preservation. Due to the high recurrence rate of APA, studies have been conducted to improve total resection of tumors. Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) improves tumor resection, but this has not been applied for APA. The patient was 35-year-old. After initial treatment, the APA lesion did not disappear. We performed hysteroscopic tumor resection using 5-ALA-PDD. Only one PDD-positive lesion was found and histopathologically diagnosed as APA. Other areas were PDD-negative and showed no histopathologic APA or malignant findings. This is the first report of hysteroscopic 5-ALA-PDD for APA. This method makes it easy to identify morbid lesions, and may lead to improved total resection and decreased recurrence.

AB - Surgical resection for atypical polypoid adenomyoma (APA) is an option for fertility preservation. Due to the high recurrence rate of APA, studies have been conducted to improve total resection of tumors. Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) improves tumor resection, but this has not been applied for APA. The patient was 35-year-old. After initial treatment, the APA lesion did not disappear. We performed hysteroscopic tumor resection using 5-ALA-PDD. Only one PDD-positive lesion was found and histopathologically diagnosed as APA. Other areas were PDD-negative and showed no histopathologic APA or malignant findings. This is the first report of hysteroscopic 5-ALA-PDD for APA. This method makes it easy to identify morbid lesions, and may lead to improved total resection and decreased recurrence.

KW - 5-Aminolevulinic acid

KW - Atypical polypoid adenomyoma

KW - Hysteroscopy

KW - Photodynamic diagnosis

UR - https://www.scopus.com/pages/publications/85068072638

UR - https://www.scopus.com/pages/publications/85068072638#tab=citedBy

U2 - 10.1016/j.pdpdt.2019.06.019

DO - 10.1016/j.pdpdt.2019.06.019

M3 - Article

C2 - 31252140

AN - SCOPUS:85068072638

SN - 1572-1000

VL - 27

SP - 295

EP - 297

JO - Photodiagnosis and Photodynamic Therapy

JF - Photodiagnosis and Photodynamic Therapy

ER -

Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid: A case report

Abstract

All Science Journal Classification (ASJC) codes

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