TY - JOUR
T1 - Autonomic manifestations in acute sensory ataxic neuropathy
T2 - A case report
AU - Ohyama, Ken
AU - Koike, Haruki
AU - Masuda, Michihito
AU - Sone, Jun
AU - Hashimoto, Rina
AU - Tomita, Minoru
AU - Kawagashira, Yuichi
AU - Iijima, Masahiro
AU - Nakamura, Tomohiko
AU - Watanabe, Hirohisa
AU - Sobue, Gen
N1 - Funding Information:
We thank Professor Susumu Kusunoki, Department of Neurology, Kinki University Faculty of Medicine, for testing the anti-ganglioside antibodies. This work was supported by grants from the Ministry of Health, Labor and Welfare and the Ministry of Education, Culture, Sports, Science and Technology of Japan .
PY - 2013/12
Y1 - 2013/12
N2 - Acute sensory ataxic neuropathy (ASAN) is known to occur with acute and monophasic sensory ataxia. Although autonomic dysfunctions have been reported, no detailed descriptions are currently available. We describe a case of ASAN in which the autonomic manifestations were systematically investigated. Although the patient did not complain of any autonomic symptoms, except for photophobia due to mydriasis, autonomic testing revealed widespread autonomic dysfunctions. Norepinephrine and dobutamine infusion test indicated the presence of sympathetic dysfunction. Additionally, the pupillary response to pilocarpine revealed the presence of parasympathetic dysfunction. In conclusion, widespread, subclinical autonomic dysfunctions may be present in ASAN patients.
AB - Acute sensory ataxic neuropathy (ASAN) is known to occur with acute and monophasic sensory ataxia. Although autonomic dysfunctions have been reported, no detailed descriptions are currently available. We describe a case of ASAN in which the autonomic manifestations were systematically investigated. Although the patient did not complain of any autonomic symptoms, except for photophobia due to mydriasis, autonomic testing revealed widespread autonomic dysfunctions. Norepinephrine and dobutamine infusion test indicated the presence of sympathetic dysfunction. Additionally, the pupillary response to pilocarpine revealed the presence of parasympathetic dysfunction. In conclusion, widespread, subclinical autonomic dysfunctions may be present in ASAN patients.
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U2 - 10.1016/j.autneu.2013.03.009
DO - 10.1016/j.autneu.2013.03.009
M3 - Article
C2 - 23598285
AN - SCOPUS:84897067206
SN - 1566-0702
VL - 179
SP - 155
EP - 158
JO - Autonomic Neuroscience: Basic and Clinical
JF - Autonomic Neuroscience: Basic and Clinical
IS - 1-2
ER -