Basics and clinical application of human mesenchymal stromal/stem cells

Yasuo Miura

doi:10.11406/rinketsu.56.2195

Basics and clinical application of human mesenchymal stromal/stem cells

Yasuo Miura

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Human mesenchymal stromal/stem cells (MSCs) show a variety of biological characteristics. The clinical trials database provided by the National Institutes of Health, USA, contains about 400 clinical trials of MSCs for a wide range of therapeutic applications internationally (http://www.clinicaltrials.gov, key words "mesenchymal stem cells", as of April, 2015). Encouraging results from these clinical trials include evidence of efficacy against graft versus host disease (GVHD) in hematopoietic stem cell transplantation. Treatment for and/or prevention of engraftment failure and insufficient hematopoietic recovery have also been explored. Herein, we will address the basic principles of MSCs and the current status of clinical studies using MSCs. Future prospects for MSC-based therapy will also be discussed.

Original language	English
Pages (from-to)	2195-2204
Number of pages	10
Journal	[Rinshō ketsueki] The Japanese journal of clinical hematology
Volume	56
Issue number	10
DOIs	https://doi.org/10.11406/rinketsu.56.2195
Publication status	Published - 01-10-2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.11406/rinketsu.56.2195

Cite this

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Basics and clinical application of human mesenchymal stromal/stem cells

Abstract

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