Behçet’s Disease with Bilateral Renal Infarction Due to Mucormycosis

Kumiko Shimoyama; Tomoyuki Niwa; Shogo Furukawa; Naomi Morishita; Yuka Nagakura; Haruka Yonezawa; Masakazu Hatakeyama; Yusuke Okubo; Daisuki Suzuki; Isao Kosugi; Kazuya Shiogama; Noriyoshi Ogawa

doi:10.2169/internalmedicine.7462-21

Behçet’s Disease with Bilateral Renal Infarction Due to Mucormycosis

Kumiko Shimoyama, Tomoyuki Niwa, Shogo Furukawa, Naomi Morishita, Yuka Nagakura, Haruka Yonezawa, Masakazu Hatakeyama, Yusuke Okubo, Daisuki Suzuki, Isao Kosugi, Kazuya Shiogama, Noriyoshi Ogawa

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

We herein report a case of Behçet’s disease with renal infarction due to mucormycosis. A 76-year-old man with entero-Behçet’s disease had been treated with glucocorticoid and tumor necrosis factor (TNF) inhibitors. His entero-Behçet’s disease was refractory to these treatments, and ileocecal resection was performed. After the operation, renal infarction that was unresponsive to anticoagulation therapy developed. He ultimately died of renal failure due to renal infarction. At the autopsy, histopathology of abundant hyphae in the renal vessel wall revealed mucormycosis. Renal mucormycosis is an important cause of renal failure with renal infarction in immunocompromised patients.

Original language	English
Pages (from-to)	1077-1083
Number of pages	7
Journal	Internal Medicine
Volume	61
Issue number	7
DOIs	https://doi.org/10.2169/internalmedicine.7462-21
Publication status	Published - 2022
Externally published	Yes

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.7462-21

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title = "Beh{\c c}et{\textquoteright}s Disease with Bilateral Renal Infarction Due to Mucormycosis",

abstract = "We herein report a case of Beh{\c c}et{\textquoteright}s disease with renal infarction due to mucormycosis. A 76-year-old man with entero-Beh{\c c}et{\textquoteright}s disease had been treated with glucocorticoid and tumor necrosis factor (TNF) inhibitors. His entero-Beh{\c c}et{\textquoteright}s disease was refractory to these treatments, and ileocecal resection was performed. After the operation, renal infarction that was unresponsive to anticoagulation therapy developed. He ultimately died of renal failure due to renal infarction. At the autopsy, histopathology of abundant hyphae in the renal vessel wall revealed mucormycosis. Renal mucormycosis is an important cause of renal failure with renal infarction in immunocompromised patients.",

author = "Kumiko Shimoyama and Tomoyuki Niwa and Shogo Furukawa and Naomi Morishita and Yuka Nagakura and Haruka Yonezawa and Masakazu Hatakeyama and Yusuke Okubo and Daisuki Suzuki and Isao Kosugi and Kazuya Shiogama and Noriyoshi Ogawa",

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doi = "10.2169/internalmedicine.7462-21",

language = "English",

volume = "61",

pages = "1077--1083",

journal = "Internal Medicine",

issn = "0918-2918",

publisher = "Japanese Society of Internal Medicine",

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TY - JOUR

T1 - Behçet’s Disease with Bilateral Renal Infarction Due to Mucormycosis

AU - Shimoyama, Kumiko

AU - Niwa, Tomoyuki

AU - Furukawa, Shogo

AU - Morishita, Naomi

AU - Nagakura, Yuka

AU - Yonezawa, Haruka

AU - Hatakeyama, Masakazu

AU - Okubo, Yusuke

AU - Suzuki, Daisuki

AU - Kosugi, Isao

AU - Shiogama, Kazuya

AU - Ogawa, Noriyoshi

PY - 2022

Y1 - 2022

N2 - We herein report a case of Behçet’s disease with renal infarction due to mucormycosis. A 76-year-old man with entero-Behçet’s disease had been treated with glucocorticoid and tumor necrosis factor (TNF) inhibitors. His entero-Behçet’s disease was refractory to these treatments, and ileocecal resection was performed. After the operation, renal infarction that was unresponsive to anticoagulation therapy developed. He ultimately died of renal failure due to renal infarction. At the autopsy, histopathology of abundant hyphae in the renal vessel wall revealed mucormycosis. Renal mucormycosis is an important cause of renal failure with renal infarction in immunocompromised patients.

AB - We herein report a case of Behçet’s disease with renal infarction due to mucormycosis. A 76-year-old man with entero-Behçet’s disease had been treated with glucocorticoid and tumor necrosis factor (TNF) inhibitors. His entero-Behçet’s disease was refractory to these treatments, and ileocecal resection was performed. After the operation, renal infarction that was unresponsive to anticoagulation therapy developed. He ultimately died of renal failure due to renal infarction. At the autopsy, histopathology of abundant hyphae in the renal vessel wall revealed mucormycosis. Renal mucormycosis is an important cause of renal failure with renal infarction in immunocompromised patients.

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VL - 61

SP - 1077

EP - 1083

JO - Internal Medicine

JF - Internal Medicine

IS - 7

ER -

Behçet’s Disease with Bilateral Renal Infarction Due to Mucormycosis

Abstract

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