Bilateral optic neuropathy associated with multiple myeloma

Yoshiaki Shimada, Masayuki Shibuya, Ryutaro Ohki, Shin Yoneya, Yuichi Nakamura

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A 51-year-old man had reduced vision and bilateral optic disc swelling as the initial clinical manifestation of multiple myeloma. Brain imaging failed to disclose any abnormalities. Before any therapy was begun, visual function began to improve substantially. Three months after chemotherapy was started, visual function and optic disc appearance returned to near normal. There were no features to suggest polyneuropathy-organomegaly-endocrinopathy-M protein-skin changes (POEMS) syndrome. Visual loss in myeloma is usually caused by compression or infiltration of the optic nerves by tumor. The mechanism of the optic neuropathy in this case remains unknown.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalJournal of Neuro-Ophthalmology
Issue number2
Publication statusPublished - 06-2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Clinical Neurology


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