Biochemical and physical analysis of subcellular membranes in rat parotid gland enlarged by chronic isoproterenol administration

Masako Mizuno, Koji Yashiro, Yasunaga Kameyama, Shigeo Hayashi, Yuzuru Sakashita, Yutaka Yokota

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

1. 1. Chronic administration of isoproterenol caused similar alterations of membrane lipid profile in at least two rat parotid subcellular fractions, secretory granular and microsomal. 2. 2. Typical changes in phospholipid classes and fatty-acyl chain groups were an increase of phosphatidylcholine and a decrease of sphingomyelin, and an increase of octadecadienoyl chain and a decreaes of eicosatetraenoyl chain, respectively. 3. 3. Electron spin resonance study showed that the isoproterenol-treatment also affected a membrane physical property, which may be through these compositional changes in membrane constituents.

Original languageEnglish
Pages (from-to)171-176
Number of pages6
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume96
Issue number1
DOIs
Publication statusPublished - 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Molecular Biology

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