Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model

Tooru Andoh; Takuya Fujimoto; Tamotsu Sudo; Minoru Suzuki; Yoshinori Sakurai; Toshiko Sakuma; Hiroshi Moritake; Tohru Sugimoto; Tamotsu Takeuchi; Hiroshi Sonobe; Alan L. Epstein; Yoshinobu Fukumori; Koji Ono; Hideki Ichikawa

doi:10.1016/j.apradiso.2013.12.007

Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model

Tooru Andoh, Takuya Fujimoto, Tamotsu Sudo, Minoru Suzuki, Yoshinori Sakurai, Toshiko Sakuma, Hiroshi Moritake, Tohru Sugimoto, Tamotsu Takeuchi, Hiroshi Sonobe, Alan L. Epstein, Yoshinobu Fukumori, Koji Ono, Hideki Ichikawa

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Clear cell sarcoma (CCS) is a rare malignant tumor with a poor prognosis. In our previous study, the tumor disappeared under boron neutron capture therapy (BNCT) on subcutaneously-transplanted CCS-bearing animals. In the present study, the tumor disappeared under this therapy on model mice intramuscularly implanted with three different human CCS cells. BNCT led to the suppression of tumor-growth in each of the different model mice, suggesting its potentiality as an alternative to, or integrative option for, the treatment of CCS.

Original language	English
Pages (from-to)	59-63
Number of pages	5
Journal	Applied Radiation and Isotopes
Volume	88
DOIs	https://doi.org/10.1016/j.apradiso.2013.12.007
Publication status	Published - 06-2014
Externally published	Yes

All Science Journal Classification (ASJC) codes

Radiation

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10.1016/j.apradiso.2013.12.007

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Andoh, T., Fujimoto, T., Sudo, T., Suzuki, M., Sakurai, Y., Sakuma, T., Moritake, H., Sugimoto, T., Takeuchi, T., Sonobe, H., Epstein, A. L., Fukumori, Y., Ono, K., & Ichikawa, H. (2014). Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model. Applied Radiation and Isotopes, 88, 59-63. https://doi.org/10.1016/j.apradiso.2013.12.007

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title = "Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model",

abstract = "Clear cell sarcoma (CCS) is a rare malignant tumor with a poor prognosis. In our previous study, the tumor disappeared under boron neutron capture therapy (BNCT) on subcutaneously-transplanted CCS-bearing animals. In the present study, the tumor disappeared under this therapy on model mice intramuscularly implanted with three different human CCS cells. BNCT led to the suppression of tumor-growth in each of the different model mice, suggesting its potentiality as an alternative to, or integrative option for, the treatment of CCS.",

author = "Tooru Andoh and Takuya Fujimoto and Tamotsu Sudo and Minoru Suzuki and Yoshinori Sakurai and Toshiko Sakuma and Hiroshi Moritake and Tohru Sugimoto and Tamotsu Takeuchi and Hiroshi Sonobe and Epstein, {Alan L.} and Yoshinobu Fukumori and Koji Ono and Hideki Ichikawa",

year = "2014",

month = jun,

doi = "10.1016/j.apradiso.2013.12.007",

language = "English",

volume = "88",

pages = "59--63",

journal = "Applied Radiation and Isotopes",

issn = "0969-8043",

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Andoh, T, Fujimoto, T, Sudo, T, Suzuki, M, Sakurai, Y, Sakuma, T, Moritake, H, Sugimoto, T, Takeuchi, T, Sonobe, H, Epstein, AL, Fukumori, Y, Ono, K & Ichikawa, H 2014, 'Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model', Applied Radiation and Isotopes, vol. 88, pp. 59-63. https://doi.org/10.1016/j.apradiso.2013.12.007

TY - JOUR

T1 - Boron neutron capture therapy as new treatment for clear cell sarcoma

T2 - Trial on different animal model

AU - Andoh, Tooru

AU - Fujimoto, Takuya

AU - Sudo, Tamotsu

AU - Suzuki, Minoru

AU - Sakurai, Yoshinori

AU - Sakuma, Toshiko

AU - Moritake, Hiroshi

AU - Sugimoto, Tohru

AU - Takeuchi, Tamotsu

AU - Sonobe, Hiroshi

AU - Epstein, Alan L.

AU - Fukumori, Yoshinobu

AU - Ono, Koji

AU - Ichikawa, Hideki

PY - 2014/6

Y1 - 2014/6

N2 - Clear cell sarcoma (CCS) is a rare malignant tumor with a poor prognosis. In our previous study, the tumor disappeared under boron neutron capture therapy (BNCT) on subcutaneously-transplanted CCS-bearing animals. In the present study, the tumor disappeared under this therapy on model mice intramuscularly implanted with three different human CCS cells. BNCT led to the suppression of tumor-growth in each of the different model mice, suggesting its potentiality as an alternative to, or integrative option for, the treatment of CCS.

AB - Clear cell sarcoma (CCS) is a rare malignant tumor with a poor prognosis. In our previous study, the tumor disappeared under boron neutron capture therapy (BNCT) on subcutaneously-transplanted CCS-bearing animals. In the present study, the tumor disappeared under this therapy on model mice intramuscularly implanted with three different human CCS cells. BNCT led to the suppression of tumor-growth in each of the different model mice, suggesting its potentiality as an alternative to, or integrative option for, the treatment of CCS.

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U2 - 10.1016/j.apradiso.2013.12.007

DO - 10.1016/j.apradiso.2013.12.007

M3 - Article

C2 - 24389062

AN - SCOPUS:84901925151

SN - 0969-8043

VL - 88

SP - 59

EP - 63

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

ER -

Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model

Abstract

All Science Journal Classification (ASJC) codes

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