Boron neutron capture therapy for clear cell sarcoma

Takuya Fujimoto; Minoru Suzuki; Tamotsu Sudo; Ikuo Fujita; Toshiko Sakuma; Yoshinori Sakurai; Takanori Hirose; Masayuki Morishita; Takushi Takata; Yuki Tamari; Hiroki Tanaka; Tooru Andoh; Teruya Kawamoto; Hitomi Hara; Naomasa Fukase; Yohei Kawakami; Rika Shigemoto; Tomoyuki Matsumoto; Hideki Ichikawa; Koji Ono; Ryosuke Kuroda; Toshihiro Akisue

doi:10.1016/j.apradiso.2020.109324

Boron neutron capture therapy for clear cell sarcoma

Takuya Fujimoto, Minoru Suzuki, Tamotsu Sudo, Ikuo Fujita, Toshiko Sakuma, Yoshinori Sakurai, Takanori Hirose, Masayuki Morishita, Takushi Takata, Yuki Tamari, Hiroki Tanaka, Tooru Andoh, Teruya Kawamoto, Hitomi Hara, Naomasa Fukase, Yohei Kawakami, Rika Shigemoto, Tomoyuki Matsumoto, Hideki Ichikawa, Koji OnoRyosuke Kuroda, Toshihiro Akisue

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Clear cell sarcoma of tendons and aponeuroses (CCS) is a rare, malignant tumor arising in lower extremities with no effective treatment other than wide surgical resection. Here described is a case of primary CCS in the peroneal tendon of the right foot of a 54-year-old woman enrolled to undergo BNCT. The tumor mass post-BNCT disappeared totally without damage to other normal tissue, demonstrating, for the first time, the potential efficacy of BNCT in complete local control of CCS.

Original language	English
Article number	109324
Journal	Applied Radiation and Isotopes
Volume	166
DOIs	https://doi.org/10.1016/j.apradiso.2020.109324
Publication status	Published - 12-2020
Externally published	Yes

All Science Journal Classification (ASJC) codes

Radiation

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Fujimoto, T., Suzuki, M., Sudo, T., Fujita, I., Sakuma, T., Sakurai, Y., Hirose, T., Morishita, M., Takata, T., Tamari, Y., Tanaka, H., Andoh, T., Kawamoto, T., Hara, H., Fukase, N., Kawakami, Y., Shigemoto, R., Matsumoto, T., Ichikawa, H., ... Akisue, T. (2020). Boron neutron capture therapy for clear cell sarcoma. Applied Radiation and Isotopes, 166, Article 109324. https://doi.org/10.1016/j.apradiso.2020.109324

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title = "Boron neutron capture therapy for clear cell sarcoma",

abstract = "Clear cell sarcoma of tendons and aponeuroses (CCS) is a rare, malignant tumor arising in lower extremities with no effective treatment other than wide surgical resection. Here described is a case of primary CCS in the peroneal tendon of the right foot of a 54-year-old woman enrolled to undergo BNCT. The tumor mass post-BNCT disappeared totally without damage to other normal tissue, demonstrating, for the first time, the potential efficacy of BNCT in complete local control of CCS.",

keywords = "Boron neutron capture therapy (BNCT), CD98, Clear cell sarcoma of tendons and aponeuroses, Clinical treatment, L-type amino acid transporter 1 (LAT1), p-borono-L-phenylalanine (BPA)",

author = "Takuya Fujimoto and Minoru Suzuki and Tamotsu Sudo and Ikuo Fujita and Toshiko Sakuma and Yoshinori Sakurai and Takanori Hirose and Masayuki Morishita and Takushi Takata and Yuki Tamari and Hiroki Tanaka and Tooru Andoh and Teruya Kawamoto and Hitomi Hara and Naomasa Fukase and Yohei Kawakami and Rika Shigemoto and Tomoyuki Matsumoto and Hideki Ichikawa and Koji Ono and Ryosuke Kuroda and Toshihiro Akisue",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

year = "2020",

month = dec,

doi = "10.1016/j.apradiso.2020.109324",

language = "English",

volume = "166",

journal = "Applied Radiation and Isotopes",

issn = "0969-8043",

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Fujimoto, T, Suzuki, M, Sudo, T, Fujita, I, Sakuma, T, Sakurai, Y, Hirose, T, Morishita, M, Takata, T, Tamari, Y, Tanaka, H, Andoh, T, Kawamoto, T, Hara, H, Fukase, N, Kawakami, Y, Shigemoto, R, Matsumoto, T, Ichikawa, H, Ono, K, Kuroda, R & Akisue, T 2020, 'Boron neutron capture therapy for clear cell sarcoma', Applied Radiation and Isotopes, vol. 166, 109324. https://doi.org/10.1016/j.apradiso.2020.109324

TY - JOUR

T1 - Boron neutron capture therapy for clear cell sarcoma

AU - Fujimoto, Takuya

AU - Suzuki, Minoru

AU - Sudo, Tamotsu

AU - Fujita, Ikuo

AU - Sakuma, Toshiko

AU - Sakurai, Yoshinori

AU - Hirose, Takanori

AU - Morishita, Masayuki

AU - Takata, Takushi

AU - Tamari, Yuki

AU - Tanaka, Hiroki

AU - Andoh, Tooru

AU - Kawamoto, Teruya

AU - Hara, Hitomi

AU - Fukase, Naomasa

AU - Kawakami, Yohei

AU - Shigemoto, Rika

AU - Matsumoto, Tomoyuki

AU - Ichikawa, Hideki

AU - Ono, Koji

AU - Kuroda, Ryosuke

AU - Akisue, Toshihiro

PY - 2020/12

Y1 - 2020/12

N2 - Clear cell sarcoma of tendons and aponeuroses (CCS) is a rare, malignant tumor arising in lower extremities with no effective treatment other than wide surgical resection. Here described is a case of primary CCS in the peroneal tendon of the right foot of a 54-year-old woman enrolled to undergo BNCT. The tumor mass post-BNCT disappeared totally without damage to other normal tissue, demonstrating, for the first time, the potential efficacy of BNCT in complete local control of CCS.

AB - Clear cell sarcoma of tendons and aponeuroses (CCS) is a rare, malignant tumor arising in lower extremities with no effective treatment other than wide surgical resection. Here described is a case of primary CCS in the peroneal tendon of the right foot of a 54-year-old woman enrolled to undergo BNCT. The tumor mass post-BNCT disappeared totally without damage to other normal tissue, demonstrating, for the first time, the potential efficacy of BNCT in complete local control of CCS.

KW - Boron neutron capture therapy (BNCT)

KW - CD98

KW - Clear cell sarcoma of tendons and aponeuroses

KW - Clinical treatment

KW - L-type amino acid transporter 1 (LAT1)

KW - p-borono-L-phenylalanine (BPA)

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U2 - 10.1016/j.apradiso.2020.109324

DO - 10.1016/j.apradiso.2020.109324

M3 - Article

C2 - 32861973

AN - SCOPUS:85089812810

SN - 0969-8043

VL - 166

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

M1 - 109324

ER -

Boron neutron capture therapy for clear cell sarcoma

Abstract

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