TY - JOUR
T1 - Budd–Chiari syndrome caused by latent hepatic metastasis from a thymoma
AU - Horiguchi, Tomoya
AU - Toyama, Yoko
AU - Sakakibara, Yosuke
AU - Ikeda, Aki
AU - Kako, Hisashi
AU - Ina, Takuma
AU - Okamura, Takuya
AU - Uozu, Sakurako
AU - Goto, Yasuhiro
AU - Yokoi, Kohei
AU - Imaizumi, Kazuyoshi
N1 - Funding Information:
We thank Ms. Naomi Maeda and Ms. Kaori Totani for their excellent secretarial support, and Ms. Chieko Oka and Ms. Noriko Hiramatsu for their technical support. We also thank Trish Reynolds, MBBS, FRACP, and H. Nikki March, PhD, from Edanz Group (https://jp.edanz.com/ac) for editing a draft of this manuscript.
Publisher Copyright:
© 2021
PY - 2021/1
Y1 - 2021/1
N2 - A 34-year-old woman visited our hospital because she had had abdominal bloating for 2 months. She had been diagnosed with invasive thymoma (WHO pathological type B2), for which she had undergone chemotherapy and total thymectomy 10 years previously. Six years previously, pleural dissemination was diagnosed and she had undergone right extra-pleural pneumonectomy. On presentation to our hospital, abdominal computed tomography and ultrasound scans revealed abundant ascites and a huge liver lesion, likely a metastasis from her thymoma, obstructing the inferior vena cava. The serum–ascites albumin gradient was high at 1.4 g/dL, which indicated portal hypertension. We diagnosed Budd–Chiari syndrome caused by liver metastasis from a previous thymoma. Steroid therapy resulted in shrinkage of her liver tumor and a marked decrease in her ascites. Although rare, Budd–Chiari syndrome caused by liver metastasis from a thymoma is a possible serious complication of advanced invasive thymoma.
AB - A 34-year-old woman visited our hospital because she had had abdominal bloating for 2 months. She had been diagnosed with invasive thymoma (WHO pathological type B2), for which she had undergone chemotherapy and total thymectomy 10 years previously. Six years previously, pleural dissemination was diagnosed and she had undergone right extra-pleural pneumonectomy. On presentation to our hospital, abdominal computed tomography and ultrasound scans revealed abundant ascites and a huge liver lesion, likely a metastasis from her thymoma, obstructing the inferior vena cava. The serum–ascites albumin gradient was high at 1.4 g/dL, which indicated portal hypertension. We diagnosed Budd–Chiari syndrome caused by liver metastasis from a previous thymoma. Steroid therapy resulted in shrinkage of her liver tumor and a marked decrease in her ascites. Although rare, Budd–Chiari syndrome caused by liver metastasis from a thymoma is a possible serious complication of advanced invasive thymoma.
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U2 - 10.1016/j.rmcr.2021.101492
DO - 10.1016/j.rmcr.2021.101492
M3 - Article
AN - SCOPUS:85111752523
SN - 2213-0071
VL - 34
JO - Respiratory Medicine Case Reports
JF - Respiratory Medicine Case Reports
M1 - 101492
ER -