Budd–Chiari syndrome caused by latent hepatic metastasis from a thymoma

Tomoya Horiguchi, Yoko Toyama, Yosuke Sakakibara, Aki Ikeda, Hisashi Kako, Takuma Ina, Takuya Okamura, Sakurako Uozu, Yasuhiro Goto, Kohei Yokoi, Kazuyoshi Imaizumi

Research output: Contribution to journalArticlepeer-review

Abstract

A 34-year-old woman visited our hospital because she had had abdominal bloating for 2 months. She had been diagnosed with invasive thymoma (WHO pathological type B2), for which she had undergone chemotherapy and total thymectomy 10 years previously. Six years previously, pleural dissemination was diagnosed and she had undergone right extra-pleural pneumonectomy. On presentation to our hospital, abdominal computed tomography and ultrasound scans revealed abundant ascites and a huge liver lesion, likely a metastasis from her thymoma, obstructing the inferior vena cava. The serum–ascites albumin gradient was high at 1.4 g/dL, which indicated portal hypertension. We diagnosed Budd–Chiari syndrome caused by liver metastasis from a previous thymoma. Steroid therapy resulted in shrinkage of her liver tumor and a marked decrease in her ascites. Although rare, Budd–Chiari syndrome caused by liver metastasis from a thymoma is a possible serious complication of advanced invasive thymoma.

Original languageEnglish
Article number101492
JournalRespiratory Medicine Case Reports
Volume34
DOIs
Publication statusPublished - 01-2021

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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