Buerger's disease in a 19-year-old woman

Masahiro Matsushita, Akihiko Kuzuya, Masayoshi Kobayashi, Naomichi Nishikimi, Masafumi Ito, Yasuhiro Oba, Takashi Yano, Kimihiro Komori

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11 Citations (Scopus)


A 19-year-old female college student had numbness and the sensation of coldness of her left toes. She had a 3-year smoking history. Gangrene of the left foot developed rapidly. Angiography revealed peripheral arterial occlusion of both legs and arms. Detailed laboratory examination excluded collagen disease, a hypercoagulable state, and juvenile atherosclerosis. Below-knee amputation of the left leg was performed. Typical histologic findings of Buerger's disease were observed in the crural arteries and saphenous veins. The clinical course was uneventful after the patient stopped smoking. This is the second case report of Buerger's disease in a woman in the second decade of life. It is important that a correct diagnosis of Buerger's disease be established, because the disease process is benign, compared with collagen disease, if the patient stops smoking.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalJournal of Vascular Surgery
Issue number1
Publication statusPublished - 07-2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Cardiology and Cardiovascular Medicine


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