TY - JOUR
T1 - Case of elderly onset possible neuro-Behçet's disease with HLA-B51 homozygosity
AU - Shiraishi, Wataru
AU - Tsujimoto, Yoshitaka
AU - Matsuyoshi, Ayano
AU - Hashimoto, Tetsuya
N1 - Publisher Copyright:
© 2023 BMJ Publishing Group. All rights reserved.
PY - 2023/6/1
Y1 - 2023/6/1
N2 - Behçet's disease commonly affects 20-40-year-old men and shows ophthalmo-dermatological manifestations. Here, we report a man in his 70s with acute onset of dysarthria, dysphagia and hemiplegia showing brainstem and subcortical lesions, which responded to steroid and colchicine therapy. He had a history of uveitis and was homozygous for the human leucocyte antigen-B51 allele, and we clinically diagnosed him with acute neuro-Behçet's disease. Old-age onset neuro-Behçet's disease is uncommon, and as far as we know, this is the oldest case of the first attack of neuro-Behçet's disease. Clinicians should consider Behçet's disease even for elderly patients.
AB - Behçet's disease commonly affects 20-40-year-old men and shows ophthalmo-dermatological manifestations. Here, we report a man in his 70s with acute onset of dysarthria, dysphagia and hemiplegia showing brainstem and subcortical lesions, which responded to steroid and colchicine therapy. He had a history of uveitis and was homozygous for the human leucocyte antigen-B51 allele, and we clinically diagnosed him with acute neuro-Behçet's disease. Old-age onset neuro-Behçet's disease is uncommon, and as far as we know, this is the oldest case of the first attack of neuro-Behçet's disease. Clinicians should consider Behçet's disease even for elderly patients.
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U2 - 10.1136/bcr-2022-252033
DO - 10.1136/bcr-2022-252033
M3 - Article
C2 - 37263675
AN - SCOPUS:85160969143
SN - 1757-790X
VL - 16
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 6
M1 - e252033
ER -