Case of elderly onset possible neuro-Behçet's disease with HLA-B51 homozygosity

Wataru Shiraishi, Yoshitaka Tsujimoto, Ayano Matsuyoshi, Tetsuya Hashimoto

Research output: Contribution to journalArticlepeer-review

Abstract

Behçet's disease commonly affects 20-40-year-old men and shows ophthalmo-dermatological manifestations. Here, we report a man in his 70s with acute onset of dysarthria, dysphagia and hemiplegia showing brainstem and subcortical lesions, which responded to steroid and colchicine therapy. He had a history of uveitis and was homozygous for the human leucocyte antigen-B51 allele, and we clinically diagnosed him with acute neuro-Behçet's disease. Old-age onset neuro-Behçet's disease is uncommon, and as far as we know, this is the oldest case of the first attack of neuro-Behçet's disease. Clinicians should consider Behçet's disease even for elderly patients.

Original languageEnglish
Article numbere252033
JournalBMJ Case Reports
Volume16
Issue number6
DOIs
Publication statusPublished - 01-06-2023
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine

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