Case of relapsed relapsed AIDS-related plasmablastic lymphoma treated with autologous srem cell transplantation and highly active antiretroviral therapy

Hiroki Goto, Shotaro Hagiwara, Risen Hirai, Takahiko Miyama, Haruhito Honda, Amane Tagashira, Toshihiko Iizuka, Makoto Mochizuki, Katsuji Teruya, Yoshimi Kikuchi, Shinichi Oka, Akiyoshi Miwa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Plasmablastic lymphoma is a rare and aggressive malignancy strongly associated with HIV infection. The refractory/relapsed disease rate is high, and the survival rate is characteristically poor. There are no satisfactory salvage regimens for relapsed cases. We successfully performed autologous stem cell transplantation using a regimen consisting of MCNU (ranimustine), etoposide, cytarabine, and melphalan in a Japanese patient with relapsed AIDS-related plasmablastic lymphoma of the oral cavity. Highly active antiretroviral therapy continued during the therapy. Therapy-related toxicity was tolerable, and a total of 40 Gy of irradiation was administered after autologous stem cell transplantation. The patient has remained in complete remission for 16 months since transplantation.

Original languageEnglish
Pages (from-to)33-35
Number of pages3
JournalRare Tumors
Volume3
Issue number1
DOIs
Publication statusPublished - 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Histology
  • Oncology

Fingerprint

Dive into the research topics of 'Case of relapsed relapsed AIDS-related plasmablastic lymphoma treated with autologous srem cell transplantation and highly active antiretroviral therapy'. Together they form a unique fingerprint.

Cite this