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Case of relapsed relapsed AIDS-related plasmablastic lymphoma treated with autologous srem cell transplantation and highly active antiretroviral therapy

  • Hiroki Goto
  • , Shotaro Hagiwara
  • , Risen Hirai
  • , Takahiko Miyama
  • , Haruhito Honda
  • , Amane Tagashira
  • , Toshihiko Iizuka
  • , Makoto Mochizuki
  • , Katsuji Teruya
  • , Yoshimi Kikuchi
  • , Shinichi Oka
  • , Akiyoshi Miwa

Research output: Contribution to journalArticlepeer-review

Abstract

Plasmablastic lymphoma is a rare and aggressive malignancy strongly associated with HIV infection. The refractory/relapsed disease rate is high, and the survival rate is characteristically poor. There are no satisfactory salvage regimens for relapsed cases. We successfully performed autologous stem cell transplantation using a regimen consisting of MCNU (ranimustine), etoposide, cytarabine, and melphalan in a Japanese patient with relapsed AIDS-related plasmablastic lymphoma of the oral cavity. Highly active antiretroviral therapy continued during the therapy. Therapy-related toxicity was tolerable, and a total of 40 Gy of irradiation was administered after autologous stem cell transplantation. The patient has remained in complete remission for 16 months since transplantation.

Original languageEnglish
Pages (from-to)33-35
Number of pages3
JournalRare Tumors
Volume3
Issue number1
DOIs
Publication statusPublished - 2011
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Histology
  • Oncology

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