Central pathology review of salivary gland adenoid cystic carcinoma

Kaori Ueda; Takayuki Murase; Toshitaka Nagao; Kimihide Kusafuka; Makoto Urano; Hidetaka Yamamoto; Masato Nakaguro; Ken ichi Taguchi; Ayako Masaki; Hideaki Hirai; Daisuke Kawakita; Kiyoaki Tsukahara; Naohito Hato; Toru Nagao; Yasushi Fujimoto; Kazuo Sakurai; Nobuhiro Hanai; Satoshi Kano; Tetsuro Onitsuka; Kenji Okami; Ken ichi Nibu; Yuichiro Tada; Ryo Kawata; Hiroshi Inagaki

doi:10.1002/hed.26081

Central pathology review of salivary gland adenoid cystic carcinoma

Kaori Ueda, Takayuki Murase, Toshitaka Nagao, Kimihide Kusafuka, Makoto Urano, Hidetaka Yamamoto, Masato Nakaguro, Ken ichi Taguchi, Ayako Masaki, Hideaki Hirai, Daisuke Kawakita, Kiyoaki Tsukahara, Naohito Hato, Toru Nagao, Yasushi Fujimoto, Kazuo Sakurai, Nobuhiro Hanai, Satoshi Kano, Tetsuro Onitsuka, Kenji OkamiKen ichi Nibu, Yuichiro Tada, Ryo Kawata, Hiroshi Inagaki

Otolaryngology

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Background: To assess the role of a central pathology review in the diagnosis of salivary gland adenoid cystic carcinoma (AdCC). Methods: Surgically resected salivary gland tumors diagnosed as AdCC (n = 219) in 15 reference hospitals in Japan were subjected to a retrospective pathological re-evaluation. Results: After the review, the AdCC diagnosis was revised in 21/219 cases (9.6%). The six benign tumors (2.7%) comprised five basal cell adenomas and one pleomorphic adenoma, and among these six patients, three received postoperative radiotherapy. The remaining 15 malignant tumors (6.8%) comprised nine basal cell adenocarcinomas and six other carcinomas. All revised basal cell adenoma/adenocarcinoma cases were of rare cribriform variants. Conclusions: A significant proportion of AdCC pathology reports were revised after the central pathology review. It should be emphasized that the greatest attention should be paid in differentiating AdCC from cribriform variant basal cell adenoma/adenocarcinoma, which is very rare in salivary gland tumors.

Original language	English
Pages (from-to)	1721-1727
Number of pages	7
Journal	Head and Neck
Volume	42
Issue number	8
DOIs	https://doi.org/10.1002/hed.26081
Publication status	Published - 01-08-2020

All Science Journal Classification (ASJC) codes

Otorhinolaryngology

Access to Document

10.1002/hed.26081

Cite this

Ueda, K., Murase, T., Nagao, T., Kusafuka, K., Urano, M., Yamamoto, H., Nakaguro, M., Taguchi, K. I., Masaki, A., Hirai, H., Kawakita, D., Tsukahara, K., Hato, N., Nagao, T., Fujimoto, Y., Sakurai, K., Hanai, N., Kano, S., Onitsuka, T., ... Inagaki, H. (2020). Central pathology review of salivary gland adenoid cystic carcinoma. Head and Neck, 42(8), 1721-1727. https://doi.org/10.1002/hed.26081

@article{194cc901ce544b4787782c6aa609214a,

title = "Central pathology review of salivary gland adenoid cystic carcinoma",

abstract = "Background: To assess the role of a central pathology review in the diagnosis of salivary gland adenoid cystic carcinoma (AdCC). Methods: Surgically resected salivary gland tumors diagnosed as AdCC (n = 219) in 15 reference hospitals in Japan were subjected to a retrospective pathological re-evaluation. Results: After the review, the AdCC diagnosis was revised in 21/219 cases (9.6%). The six benign tumors (2.7%) comprised five basal cell adenomas and one pleomorphic adenoma, and among these six patients, three received postoperative radiotherapy. The remaining 15 malignant tumors (6.8%) comprised nine basal cell adenocarcinomas and six other carcinomas. All revised basal cell adenoma/adenocarcinoma cases were of rare cribriform variants. Conclusions: A significant proportion of AdCC pathology reports were revised after the central pathology review. It should be emphasized that the greatest attention should be paid in differentiating AdCC from cribriform variant basal cell adenoma/adenocarcinoma, which is very rare in salivary gland tumors.",

keywords = "adenoid cystic carcinoma, basal cell adenoma/basal cell adenocarcinoma, central pathology review, cribriform variant, salivary gland",

author = "Kaori Ueda and Takayuki Murase and Toshitaka Nagao and Kimihide Kusafuka and Makoto Urano and Hidetaka Yamamoto and Masato Nakaguro and Taguchi, {Ken ichi} and Ayako Masaki and Hideaki Hirai and Daisuke Kawakita and Kiyoaki Tsukahara and Naohito Hato and Toru Nagao and Yasushi Fujimoto and Kazuo Sakurai and Nobuhiro Hanai and Satoshi Kano and Tetsuro Onitsuka and Kenji Okami and Nibu, {Ken ichi} and Yuichiro Tada and Ryo Kawata and Hiroshi Inagaki",

note = "Publisher Copyright: {\textcopyright} 2020 Wiley Periodicals, Inc.",

year = "2020",

month = aug,

day = "1",

doi = "10.1002/hed.26081",

language = "English",

volume = "42",

pages = "1721--1727",

journal = "Head and Neck",

issn = "1043-3074",

publisher = "John Wiley & Sons Inc.",

number = "8",

}

Ueda, K, Murase, T, Nagao, T, Kusafuka, K, Urano, M, Yamamoto, H, Nakaguro, M, Taguchi, KI, Masaki, A, Hirai, H, Kawakita, D, Tsukahara, K, Hato, N, Nagao, T, Fujimoto, Y, Sakurai, K, Hanai, N, Kano, S, Onitsuka, T, Okami, K, Nibu, KI, Tada, Y, Kawata, R & Inagaki, H 2020, 'Central pathology review of salivary gland adenoid cystic carcinoma', Head and Neck, vol. 42, no. 8, pp. 1721-1727. https://doi.org/10.1002/hed.26081

TY - JOUR

T1 - Central pathology review of salivary gland adenoid cystic carcinoma

AU - Ueda, Kaori

AU - Murase, Takayuki

AU - Nagao, Toshitaka

AU - Kusafuka, Kimihide

AU - Urano, Makoto

AU - Yamamoto, Hidetaka

AU - Nakaguro, Masato

AU - Taguchi, Ken ichi

AU - Masaki, Ayako

AU - Hirai, Hideaki

AU - Kawakita, Daisuke

AU - Tsukahara, Kiyoaki

AU - Hato, Naohito

AU - Nagao, Toru

AU - Fujimoto, Yasushi

AU - Sakurai, Kazuo

AU - Hanai, Nobuhiro

AU - Kano, Satoshi

AU - Onitsuka, Tetsuro

AU - Okami, Kenji

AU - Nibu, Ken ichi

AU - Tada, Yuichiro

AU - Kawata, Ryo

AU - Inagaki, Hiroshi

PY - 2020/8/1

Y1 - 2020/8/1

N2 - Background: To assess the role of a central pathology review in the diagnosis of salivary gland adenoid cystic carcinoma (AdCC). Methods: Surgically resected salivary gland tumors diagnosed as AdCC (n = 219) in 15 reference hospitals in Japan were subjected to a retrospective pathological re-evaluation. Results: After the review, the AdCC diagnosis was revised in 21/219 cases (9.6%). The six benign tumors (2.7%) comprised five basal cell adenomas and one pleomorphic adenoma, and among these six patients, three received postoperative radiotherapy. The remaining 15 malignant tumors (6.8%) comprised nine basal cell adenocarcinomas and six other carcinomas. All revised basal cell adenoma/adenocarcinoma cases were of rare cribriform variants. Conclusions: A significant proportion of AdCC pathology reports were revised after the central pathology review. It should be emphasized that the greatest attention should be paid in differentiating AdCC from cribriform variant basal cell adenoma/adenocarcinoma, which is very rare in salivary gland tumors.

AB - Background: To assess the role of a central pathology review in the diagnosis of salivary gland adenoid cystic carcinoma (AdCC). Methods: Surgically resected salivary gland tumors diagnosed as AdCC (n = 219) in 15 reference hospitals in Japan were subjected to a retrospective pathological re-evaluation. Results: After the review, the AdCC diagnosis was revised in 21/219 cases (9.6%). The six benign tumors (2.7%) comprised five basal cell adenomas and one pleomorphic adenoma, and among these six patients, three received postoperative radiotherapy. The remaining 15 malignant tumors (6.8%) comprised nine basal cell adenocarcinomas and six other carcinomas. All revised basal cell adenoma/adenocarcinoma cases were of rare cribriform variants. Conclusions: A significant proportion of AdCC pathology reports were revised after the central pathology review. It should be emphasized that the greatest attention should be paid in differentiating AdCC from cribriform variant basal cell adenoma/adenocarcinoma, which is very rare in salivary gland tumors.

KW - adenoid cystic carcinoma

KW - basal cell adenoma/basal cell adenocarcinoma

KW - central pathology review

KW - cribriform variant

KW - salivary gland

UR - http://www.scopus.com/inward/record.url?scp=85078720768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85078720768&partnerID=8YFLogxK

U2 - 10.1002/hed.26081

DO - 10.1002/hed.26081

M3 - Article

C2 - 31970840

AN - SCOPUS:85078720768

SN - 1043-3074

VL - 42

SP - 1721

EP - 1727

JO - Head and Neck

JF - Head and Neck

IS - 8

ER -

Central pathology review of salivary gland adenoid cystic carcinoma

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this