@article{194cc901ce544b4787782c6aa609214a,
title = "Central pathology review of salivary gland adenoid cystic carcinoma",
abstract = "Background: To assess the role of a central pathology review in the diagnosis of salivary gland adenoid cystic carcinoma (AdCC). Methods: Surgically resected salivary gland tumors diagnosed as AdCC (n = 219) in 15 reference hospitals in Japan were subjected to a retrospective pathological re-evaluation. Results: After the review, the AdCC diagnosis was revised in 21/219 cases (9.6%). The six benign tumors (2.7%) comprised five basal cell adenomas and one pleomorphic adenoma, and among these six patients, three received postoperative radiotherapy. The remaining 15 malignant tumors (6.8%) comprised nine basal cell adenocarcinomas and six other carcinomas. All revised basal cell adenoma/adenocarcinoma cases were of rare cribriform variants. Conclusions: A significant proportion of AdCC pathology reports were revised after the central pathology review. It should be emphasized that the greatest attention should be paid in differentiating AdCC from cribriform variant basal cell adenoma/adenocarcinoma, which is very rare in salivary gland tumors.",
author = "Kaori Ueda and Takayuki Murase and Toshitaka Nagao and Kimihide Kusafuka and Makoto Urano and Hidetaka Yamamoto and Masato Nakaguro and Taguchi, {Ken ichi} and Ayako Masaki and Hideaki Hirai and Daisuke Kawakita and Kiyoaki Tsukahara and Naohito Hato and Toru Nagao and Yasushi Fujimoto and Kazuo Sakurai and Nobuhiro Hanai and Satoshi Kano and Tetsuro Onitsuka and Kenji Okami and Nibu, {Ken ichi} and Yuichiro Tada and Ryo Kawata and Hiroshi Inagaki",
note = "Funding Information: This work was supported by grants-in-aid for scientific research, MEXT, Japan (No. 16H04713 to HI and 17 K08746 to TM). The authors thank Drs Kana Tsuda and Yuma Sakamoto, Nagoya City University, for their valuable comments. The authors also thank Drs Yoshihide Okumura, Kosuke Saida, and Yohei Ito, Nagoya City University, for their secretarial assistance to the Study Group. K Ueda and T Murase contributed equally to this work. Funding Information: This work was supported by grants‐in‐aid for scientific research, MEXT, Japan (No. 16H04713 to HI and 17 K08746 to TM). The authors thank Drs Kana Tsuda and Yuma Sakamoto, Nagoya City University, for their valuable comments. The authors also thank Drs Yoshihide Okumura, Kosuke Saida, and Yohei Ito, Nagoya City University, for their secretarial assistance to the Study Group. K Ueda and T Murase contributed equally to this work. Publisher Copyright: {\textcopyright} 2020 Wiley Periodicals, Inc.",
year = "2020",
month = aug,
day = "1",
doi = "10.1002/hed.26081",
language = "English",
volume = "42",
pages = "1721--1727",
journal = "Head and Neck",
issn = "1043-3074",
publisher = "John Wiley and Sons Inc.",
number = "8",
}