Cerebellar gliofibroma with numerous psammoma bodies

Motohiro Nomura; Mitsuhiro Hasegawa; Daisuke Kita; Junkoh Yamashita; Hiroshi Minato; Yoichi Nakazato

doi:10.1016/j.clineuro.2005.01.013

Cerebellar gliofibroma with numerous psammoma bodies

Motohiro Nomura, Mitsuhiro Hasegawa, Daisuke Kita, Junkoh Yamashita, Hiroshi Minato, Yoichi Nakazato

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A case of psammoma body rich gliofibroma is reported. Computed tomography (CT) showed a high-density mass without contrast enhancement in the right cerebellar hemisphere. Magnetic resonance images (MRI) demonstrated a mass with a mixture of high- and iso-intensity regions without meningeal attachment on both T1- and T2-weighted images. Pathological examinations revealed a biphasic pattern consisting of tumor cells in sparce cellularity and dense fibrous connective tissue. Numerous psammoma bodies of uniform size were found in the stroma. The tumor cells expressed glial fibrillary acidic protein and S-100, but not p53, vimentin and EMA. This is the first report describing a case of psammomatous gliofibroma.

Original language	English
Pages (from-to)	421-425
Number of pages	5
Journal	Clinical Neurology and Neurosurgery
Volume	108
Issue number	4
DOIs	https://doi.org/10.1016/j.clineuro.2005.01.013
Publication status	Published - 01-06-2006
Externally published	Yes

All Science Journal Classification (ASJC) codes

Surgery
Clinical Neurology

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10.1016/j.clineuro.2005.01.013

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title = "Cerebellar gliofibroma with numerous psammoma bodies",

abstract = "A case of psammoma body rich gliofibroma is reported. Computed tomography (CT) showed a high-density mass without contrast enhancement in the right cerebellar hemisphere. Magnetic resonance images (MRI) demonstrated a mass with a mixture of high- and iso-intensity regions without meningeal attachment on both T1- and T2-weighted images. Pathological examinations revealed a biphasic pattern consisting of tumor cells in sparce cellularity and dense fibrous connective tissue. Numerous psammoma bodies of uniform size were found in the stroma. The tumor cells expressed glial fibrillary acidic protein and S-100, but not p53, vimentin and EMA. This is the first report describing a case of psammomatous gliofibroma.",

author = "Motohiro Nomura and Mitsuhiro Hasegawa and Daisuke Kita and Junkoh Yamashita and Hiroshi Minato and Yoichi Nakazato",

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T1 - Cerebellar gliofibroma with numerous psammoma bodies

AU - Nomura, Motohiro

AU - Hasegawa, Mitsuhiro

AU - Kita, Daisuke

AU - Yamashita, Junkoh

AU - Minato, Hiroshi

AU - Nakazato, Yoichi

PY - 2006/6/1

Y1 - 2006/6/1

N2 - A case of psammoma body rich gliofibroma is reported. Computed tomography (CT) showed a high-density mass without contrast enhancement in the right cerebellar hemisphere. Magnetic resonance images (MRI) demonstrated a mass with a mixture of high- and iso-intensity regions without meningeal attachment on both T1- and T2-weighted images. Pathological examinations revealed a biphasic pattern consisting of tumor cells in sparce cellularity and dense fibrous connective tissue. Numerous psammoma bodies of uniform size were found in the stroma. The tumor cells expressed glial fibrillary acidic protein and S-100, but not p53, vimentin and EMA. This is the first report describing a case of psammomatous gliofibroma.

AB - A case of psammoma body rich gliofibroma is reported. Computed tomography (CT) showed a high-density mass without contrast enhancement in the right cerebellar hemisphere. Magnetic resonance images (MRI) demonstrated a mass with a mixture of high- and iso-intensity regions without meningeal attachment on both T1- and T2-weighted images. Pathological examinations revealed a biphasic pattern consisting of tumor cells in sparce cellularity and dense fibrous connective tissue. Numerous psammoma bodies of uniform size were found in the stroma. The tumor cells expressed glial fibrillary acidic protein and S-100, but not p53, vimentin and EMA. This is the first report describing a case of psammomatous gliofibroma.

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