Cerebral hemodynamics in patients with chronic obstructive carotid disease by rCBF, rCBV, and rCBV/rCBF ratio using SPECT

Hiroshi Toyama, G. Takeshita, A. Takeuchi, H. Anno, K. Ejiri, H. Maeda, K. Katada, S. Koga, N. Ishiyama, T. Kanno, N. Yamaoka

Research output: Contribution to journalArticle

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Abstract

To evaluate cerebral hemodynamics, 21 patients with chronic occlusion or severe stenosis of the internal carotid or middle cerebral artery with normal or only lacunar infarction on x-ray CT were studied using single photon emission computed tomography (SPECT). We measured rCBV with 99mTc erythrocytes after rCBF with 133Xe, and calculated rCBV/rCBF. rCBF and rCBV of the 25 affected hemispheres were classified as (a) patients with normal rCBF →type I (n = 7) and type II (n = 3)←; (b) patients with decreased rCBF →type III (n = 6) and type IV (n = 9)←. These two groups then could be subdivided according to findings of rCBV, normal, and increased blood volumes. rCBV/rCBF increased as the cerebral perfusion pressure dropped from type I to type III. In type IV, other situations but cerebral autoregulation could be assumed. rCBV/rCBF signifies vascular mean transit time. Type III (high rCBV/rCBF) assumed as the increased OEF, misery perfusion as reported in PET. We propose rCBF, rCBV and rCBV/rCBF using SPECT can be an index for cerebral circulatory reserve.

Original languageEnglish
Pages (from-to)55-60
Number of pages6
JournalJournal of Nuclear Medicine
Volume31
Issue number1
Publication statusPublished - 01-01-1990

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Single-Photon Emission-Computed Tomography
Hemodynamics
Cerebrovascular Circulation
Lacunar Stroke
Carotid Stenosis
Middle Cerebral Artery
Blood Volume
Blood Vessels
Homeostasis
Perfusion
Erythrocytes
X-Rays

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Toyama, Hiroshi ; Takeshita, G. ; Takeuchi, A. ; Anno, H. ; Ejiri, K. ; Maeda, H. ; Katada, K. ; Koga, S. ; Ishiyama, N. ; Kanno, T. ; Yamaoka, N. / Cerebral hemodynamics in patients with chronic obstructive carotid disease by rCBF, rCBV, and rCBV/rCBF ratio using SPECT. In: Journal of Nuclear Medicine. 1990 ; Vol. 31, No. 1. pp. 55-60.
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abstract = "To evaluate cerebral hemodynamics, 21 patients with chronic occlusion or severe stenosis of the internal carotid or middle cerebral artery with normal or only lacunar infarction on x-ray CT were studied using single photon emission computed tomography (SPECT). We measured rCBV with 99mTc erythrocytes after rCBF with 133Xe, and calculated rCBV/rCBF. rCBF and rCBV of the 25 affected hemispheres were classified as (a) patients with normal rCBF →type I (n = 7) and type II (n = 3)←; (b) patients with decreased rCBF →type III (n = 6) and type IV (n = 9)←. These two groups then could be subdivided according to findings of rCBV, normal, and increased blood volumes. rCBV/rCBF increased as the cerebral perfusion pressure dropped from type I to type III. In type IV, other situations but cerebral autoregulation could be assumed. rCBV/rCBF signifies vascular mean transit time. Type III (high rCBV/rCBF) assumed as the increased OEF, misery perfusion as reported in PET. We propose rCBF, rCBV and rCBV/rCBF using SPECT can be an index for cerebral circulatory reserve.",
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Toyama, H, Takeshita, G, Takeuchi, A, Anno, H, Ejiri, K, Maeda, H, Katada, K, Koga, S, Ishiyama, N, Kanno, T & Yamaoka, N 1990, 'Cerebral hemodynamics in patients with chronic obstructive carotid disease by rCBF, rCBV, and rCBV/rCBF ratio using SPECT', Journal of Nuclear Medicine, vol. 31, no. 1, pp. 55-60.

Cerebral hemodynamics in patients with chronic obstructive carotid disease by rCBF, rCBV, and rCBV/rCBF ratio using SPECT. / Toyama, Hiroshi; Takeshita, G.; Takeuchi, A.; Anno, H.; Ejiri, K.; Maeda, H.; Katada, K.; Koga, S.; Ishiyama, N.; Kanno, T.; Yamaoka, N.

In: Journal of Nuclear Medicine, Vol. 31, No. 1, 01.01.1990, p. 55-60.

Research output: Contribution to journalArticle

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T1 - Cerebral hemodynamics in patients with chronic obstructive carotid disease by rCBF, rCBV, and rCBV/rCBF ratio using SPECT

AU - Toyama, Hiroshi

AU - Takeshita, G.

AU - Takeuchi, A.

AU - Anno, H.

AU - Ejiri, K.

AU - Maeda, H.

AU - Katada, K.

AU - Koga, S.

AU - Ishiyama, N.

AU - Kanno, T.

AU - Yamaoka, N.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - To evaluate cerebral hemodynamics, 21 patients with chronic occlusion or severe stenosis of the internal carotid or middle cerebral artery with normal or only lacunar infarction on x-ray CT were studied using single photon emission computed tomography (SPECT). We measured rCBV with 99mTc erythrocytes after rCBF with 133Xe, and calculated rCBV/rCBF. rCBF and rCBV of the 25 affected hemispheres were classified as (a) patients with normal rCBF →type I (n = 7) and type II (n = 3)←; (b) patients with decreased rCBF →type III (n = 6) and type IV (n = 9)←. These two groups then could be subdivided according to findings of rCBV, normal, and increased blood volumes. rCBV/rCBF increased as the cerebral perfusion pressure dropped from type I to type III. In type IV, other situations but cerebral autoregulation could be assumed. rCBV/rCBF signifies vascular mean transit time. Type III (high rCBV/rCBF) assumed as the increased OEF, misery perfusion as reported in PET. We propose rCBF, rCBV and rCBV/rCBF using SPECT can be an index for cerebral circulatory reserve.

AB - To evaluate cerebral hemodynamics, 21 patients with chronic occlusion or severe stenosis of the internal carotid or middle cerebral artery with normal or only lacunar infarction on x-ray CT were studied using single photon emission computed tomography (SPECT). We measured rCBV with 99mTc erythrocytes after rCBF with 133Xe, and calculated rCBV/rCBF. rCBF and rCBV of the 25 affected hemispheres were classified as (a) patients with normal rCBF →type I (n = 7) and type II (n = 3)←; (b) patients with decreased rCBF →type III (n = 6) and type IV (n = 9)←. These two groups then could be subdivided according to findings of rCBV, normal, and increased blood volumes. rCBV/rCBF increased as the cerebral perfusion pressure dropped from type I to type III. In type IV, other situations but cerebral autoregulation could be assumed. rCBV/rCBF signifies vascular mean transit time. Type III (high rCBV/rCBF) assumed as the increased OEF, misery perfusion as reported in PET. We propose rCBF, rCBV and rCBV/rCBF using SPECT can be an index for cerebral circulatory reserve.

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M3 - Article

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