TY - JOUR
T1 - Changes in striatal dopamine release in stress-induced conditioned suppression of motility in rats
AU - Katoh, Akira
AU - Nabeshima, Toshitaka
AU - Kuno, Ayako
AU - Wada, Masako
AU - Ukai, Reiko
AU - Kameyama, Tsutomu
PY - 1996/5
Y1 - 1996/5
N2 - Rats received a footshock for 10 min in a chamber with a metallic grid floor, and then placed into the chamber for 30 min after 6 days. The motility of the shocked rats showed a significant decrease (conditioned suppression of motility). In addition, the extracellular dopamine (DA) levels in the striatum were also reduced significantly in in vivo microdialysis study. Thus, dysfunction in the striatal DAergic neuronal systems is responsible for mental stress responses such as conditioned fear stress.
AB - Rats received a footshock for 10 min in a chamber with a metallic grid floor, and then placed into the chamber for 30 min after 6 days. The motility of the shocked rats showed a significant decrease (conditioned suppression of motility). In addition, the extracellular dopamine (DA) levels in the striatum were also reduced significantly in in vivo microdialysis study. Thus, dysfunction in the striatal DAergic neuronal systems is responsible for mental stress responses such as conditioned fear stress.
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U2 - 10.1016/0166-4328(95)00228-6
DO - 10.1016/0166-4328(95)00228-6
M3 - Article
C2 - 8762174
AN - SCOPUS:0029938131
SN - 0166-4328
VL - 77
SP - 219
EP - 221
JO - Behavioural Brain Research
JF - Behavioural Brain Research
IS - 1-2
ER -