Changes in striatal dopamine release in stress-induced conditioned suppression of motility in rats

Akira Katoh, Toshitaka Nabeshima, Ayako Kuno, Masako Wada, Reiko Ukai, Tsutomu Kameyama

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Rats received a footshock for 10 min in a chamber with a metallic grid floor, and then placed into the chamber for 30 min after 6 days. The motility of the shocked rats showed a significant decrease (conditioned suppression of motility). In addition, the extracellular dopamine (DA) levels in the striatum were also reduced significantly in in vivo microdialysis study. Thus, dysfunction in the striatal DAergic neuronal systems is responsible for mental stress responses such as conditioned fear stress.

Original languageEnglish
Pages (from-to)219-221
Number of pages3
JournalBehavioural Brain Research
Volume77
Issue number1-2
DOIs
Publication statusPublished - 05-1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Behavioral Neuroscience

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