TY - JOUR
T1 - Changes in the peripheral eosinophil count in patients with acute eosinophilic myocarditis
AU - Morimoto, Shin Ichiro
AU - Kubo, Natsuko
AU - Hiramitsu, Shinya
AU - Uemura, Akihisa
AU - Ohtsuki, Masatsugu
AU - Kato, Shigeru
AU - Kato, Yasuchika
AU - Sugiura, Atsushi
AU - Miyagishima, Kenji
AU - Mori, Nami
AU - Yoshida, Yukihiko
AU - Hishida, Hitoshi
PY - 2003/9
Y1 - 2003/9
N2 - In many cases, the diagnosis of eosinophilic myocarditis is suggested by an elevated peripheral blood eosinophil count. However, no detailed studies have been performed on the sequential changes in the initial peripheral blood eosinophil count over the course of the disease. We measured the peripheral blood eosinophil count at the time of presentation in eight patients with eosinophilic myocarditis proven by endomyocardial biopsy and intermittently thereafter. The eosinophil count at the time of onset was <500/mm3 in four patients, >500/mm3 but <1000/mm3 in three patients, and ≧1000/mm3 in one patient. In three of the four patients with an initial eosinophil count of <500/mm3, an increase to ≧500/mm3 occurred 7-12 days after the onset. The remaining patient did not develop peripheral eosinophilia. In conclusion, in the early stage of eosinophilic myocarditis, peripheral hypereosinophilia is not present initially in some patients, and may not develop during the course of the illness in a subset of these patients.
AB - In many cases, the diagnosis of eosinophilic myocarditis is suggested by an elevated peripheral blood eosinophil count. However, no detailed studies have been performed on the sequential changes in the initial peripheral blood eosinophil count over the course of the disease. We measured the peripheral blood eosinophil count at the time of presentation in eight patients with eosinophilic myocarditis proven by endomyocardial biopsy and intermittently thereafter. The eosinophil count at the time of onset was <500/mm3 in four patients, >500/mm3 but <1000/mm3 in three patients, and ≧1000/mm3 in one patient. In three of the four patients with an initial eosinophil count of <500/mm3, an increase to ≧500/mm3 occurred 7-12 days after the onset. The remaining patient did not develop peripheral eosinophilia. In conclusion, in the early stage of eosinophilic myocarditis, peripheral hypereosinophilia is not present initially in some patients, and may not develop during the course of the illness in a subset of these patients.
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U2 - 10.1007/s00380-003-0721-0
DO - 10.1007/s00380-003-0721-0
M3 - Article
C2 - 14520487
AN - SCOPUS:10744230602
SN - 0910-8327
VL - 18
SP - 193
EP - 196
JO - Heart and Vessels
JF - Heart and Vessels
IS - 4
ER -