Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project

BioBank Japan Cooperative Hospital Group

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively. Methods: Of all Japanese male and female lung cancer patients aged ≥ 20 years whom the BioBank Japan Project originally enrolled between 2003 and 2008, 764 males and 415 females were registered within 90 days after their diagnosis. We described the lifestyle and clinical characteristics of these patients at study entry. Furthermore, we examined the effect of these characteristics on all-cause mortality. Results: In the lung cancer patients registered within 90 days, the frequencies of occult or stage 0, stage I, II, III and IV were 0.4%, 55.8%, 10.8%, 22.0% and 11.0% for males and 0.3%, 62.4%, 9.9%, 17.1% and 10.2% for females, respectively. The proportions of histological types in males and females were 56.3% and 82.4% for adenocarcinoma, 26.9% and 8.2% for squamous cell carcinoma, 4.5% and 1.5% for large cell carcinoma, 7.7% and 4.1% for small cell carcinoma and 4.6% and 3.8% for others, respectively. Among 1120 participants who registered within 90 days, 572 participants died during 5811 person-years of follow-up. Low body mass index, ever smoker, more advanced stage, squamous cell or small cell carcinoma and high serum carcinoembryonic antigen level at study entry were crudely associated with an increased risk of all-cause mortality after adjustment for age. Conclusions: This study showed the association of several lifestyle and clinical characteristics with allcause mortality in lung cancer patients.

Original languageEnglish
Pages (from-to)S49-S57
JournalJournal of epidemiology
Volume27
Issue number3
DOIs
Publication statusPublished - 01-01-2017

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Lung Neoplasms
Japan
Small Cell Carcinoma
Mortality
Life Style
Large Cell Carcinoma
Second Primary Neoplasms
Carcinoembryonic Antigen
Squamous Cell Carcinoma
Adenocarcinoma
Body Mass Index
Epithelial Cells
Serum
Neoplasms

All Science Journal Classification (ASJC) codes

  • Epidemiology

Cite this

BioBank Japan Cooperative Hospital Group. / Characteristics and prognosis of Japanese male and female lung cancer patients : The BioBank Japan Project. In: Journal of epidemiology. 2017 ; Vol. 27, No. 3. pp. S49-S57.
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title = "Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project",
abstract = "Background: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively. Methods: Of all Japanese male and female lung cancer patients aged ≥ 20 years whom the BioBank Japan Project originally enrolled between 2003 and 2008, 764 males and 415 females were registered within 90 days after their diagnosis. We described the lifestyle and clinical characteristics of these patients at study entry. Furthermore, we examined the effect of these characteristics on all-cause mortality. Results: In the lung cancer patients registered within 90 days, the frequencies of occult or stage 0, stage I, II, III and IV were 0.4{\%}, 55.8{\%}, 10.8{\%}, 22.0{\%} and 11.0{\%} for males and 0.3{\%}, 62.4{\%}, 9.9{\%}, 17.1{\%} and 10.2{\%} for females, respectively. The proportions of histological types in males and females were 56.3{\%} and 82.4{\%} for adenocarcinoma, 26.9{\%} and 8.2{\%} for squamous cell carcinoma, 4.5{\%} and 1.5{\%} for large cell carcinoma, 7.7{\%} and 4.1{\%} for small cell carcinoma and 4.6{\%} and 3.8{\%} for others, respectively. Among 1120 participants who registered within 90 days, 572 participants died during 5811 person-years of follow-up. Low body mass index, ever smoker, more advanced stage, squamous cell or small cell carcinoma and high serum carcinoembryonic antigen level at study entry were crudely associated with an increased risk of all-cause mortality after adjustment for age. Conclusions: This study showed the association of several lifestyle and clinical characteristics with allcause mortality in lung cancer patients.",
author = "{BioBank Japan Cooperative Hospital Group} and Koshi Nakamura and Shigekazu Ukawa and Emiko Okada and Makoto Hirata and Akiko Nagai and Zentaro Yamagata and Toshiharu Ninomiya and Kaori Muto and Yutaka Kiyohara and Koichi Matsuda and Yoichiro Kamatani and Michiaki Kubo and Yusuke Nakamura and Akiko Tamakoshi and Hiromasa Harada and Makoto Hibino and Atsushi Okuyama and Nobuyasu Kano and Shiro Minami and Akihiko Genma and Jitsuo Usuda and Kenji Suzuki and Mitsuaki Sekiya and Satoru Takeda and Satoshi Asai and Mitsuhiko Moriyama and Yasuo Takahashi and Tomoaki Fujioka and Wataru Obara and Seijiro Mori and Hideki Ito and Satoshi Nagayama and Yoshio Miki and Akihide Masumoto and Akira Yamada and Yasuko Nishizawa and Ken Kodama and Noriaki Tezuka and Yasutaka Nakano and Yukihiro Koretsune and Mitsumasa Ogawara and Kazunari Yamana",
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Characteristics and prognosis of Japanese male and female lung cancer patients : The BioBank Japan Project. / BioBank Japan Cooperative Hospital Group.

In: Journal of epidemiology, Vol. 27, No. 3, 01.01.2017, p. S49-S57.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Characteristics and prognosis of Japanese male and female lung cancer patients

T2 - The BioBank Japan Project

AU - BioBank Japan Cooperative Hospital Group

AU - Nakamura, Koshi

AU - Ukawa, Shigekazu

AU - Okada, Emiko

AU - Hirata, Makoto

AU - Nagai, Akiko

AU - Yamagata, Zentaro

AU - Ninomiya, Toshiharu

AU - Muto, Kaori

AU - Kiyohara, Yutaka

AU - Matsuda, Koichi

AU - Kamatani, Yoichiro

AU - Kubo, Michiaki

AU - Nakamura, Yusuke

AU - Tamakoshi, Akiko

AU - Harada, Hiromasa

AU - Hibino, Makoto

AU - Okuyama, Atsushi

AU - Kano, Nobuyasu

AU - Minami, Shiro

AU - Genma, Akihiko

AU - Usuda, Jitsuo

AU - Suzuki, Kenji

AU - Sekiya, Mitsuaki

AU - Takeda, Satoru

AU - Asai, Satoshi

AU - Moriyama, Mitsuhiko

AU - Takahashi, Yasuo

AU - Fujioka, Tomoaki

AU - Obara, Wataru

AU - Mori, Seijiro

AU - Ito, Hideki

AU - Nagayama, Satoshi

AU - Miki, Yoshio

AU - Masumoto, Akihide

AU - Yamada, Akira

AU - Nishizawa, Yasuko

AU - Kodama, Ken

AU - Tezuka, Noriaki

AU - Nakano, Yasutaka

AU - Koretsune, Yukihiro

AU - Ogawara, Mitsumasa

AU - Yamana, Kazunari

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Background: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively. Methods: Of all Japanese male and female lung cancer patients aged ≥ 20 years whom the BioBank Japan Project originally enrolled between 2003 and 2008, 764 males and 415 females were registered within 90 days after their diagnosis. We described the lifestyle and clinical characteristics of these patients at study entry. Furthermore, we examined the effect of these characteristics on all-cause mortality. Results: In the lung cancer patients registered within 90 days, the frequencies of occult or stage 0, stage I, II, III and IV were 0.4%, 55.8%, 10.8%, 22.0% and 11.0% for males and 0.3%, 62.4%, 9.9%, 17.1% and 10.2% for females, respectively. The proportions of histological types in males and females were 56.3% and 82.4% for adenocarcinoma, 26.9% and 8.2% for squamous cell carcinoma, 4.5% and 1.5% for large cell carcinoma, 7.7% and 4.1% for small cell carcinoma and 4.6% and 3.8% for others, respectively. Among 1120 participants who registered within 90 days, 572 participants died during 5811 person-years of follow-up. Low body mass index, ever smoker, more advanced stage, squamous cell or small cell carcinoma and high serum carcinoembryonic antigen level at study entry were crudely associated with an increased risk of all-cause mortality after adjustment for age. Conclusions: This study showed the association of several lifestyle and clinical characteristics with allcause mortality in lung cancer patients.

AB - Background: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively. Methods: Of all Japanese male and female lung cancer patients aged ≥ 20 years whom the BioBank Japan Project originally enrolled between 2003 and 2008, 764 males and 415 females were registered within 90 days after their diagnosis. We described the lifestyle and clinical characteristics of these patients at study entry. Furthermore, we examined the effect of these characteristics on all-cause mortality. Results: In the lung cancer patients registered within 90 days, the frequencies of occult or stage 0, stage I, II, III and IV were 0.4%, 55.8%, 10.8%, 22.0% and 11.0% for males and 0.3%, 62.4%, 9.9%, 17.1% and 10.2% for females, respectively. The proportions of histological types in males and females were 56.3% and 82.4% for adenocarcinoma, 26.9% and 8.2% for squamous cell carcinoma, 4.5% and 1.5% for large cell carcinoma, 7.7% and 4.1% for small cell carcinoma and 4.6% and 3.8% for others, respectively. Among 1120 participants who registered within 90 days, 572 participants died during 5811 person-years of follow-up. Low body mass index, ever smoker, more advanced stage, squamous cell or small cell carcinoma and high serum carcinoembryonic antigen level at study entry were crudely associated with an increased risk of all-cause mortality after adjustment for age. Conclusions: This study showed the association of several lifestyle and clinical characteristics with allcause mortality in lung cancer patients.

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U2 - 10.1016/j.je.2016.12.010

DO - 10.1016/j.je.2016.12.010

M3 - Article

C2 - 28202209

AN - SCOPUS:85016415031

VL - 27

SP - S49-S57

JO - Journal of Epidemiology

JF - Journal of Epidemiology

SN - 0917-5040

IS - 3

ER -