TY - JOUR
T1 - Characterization of an unusual DS-1-like G8P[8] rotavirus strain from Japan in 2017
T2 - Evolution of emerging DS-1-like G8P[8] strains through reassortment
AU - Kamiya, Hajime
AU - Tacharoenmuang, Ratana
AU - Ide, Tomihiko
AU - Negoro, Manami
AU - Tanaka, Takaaki
AU - Asada, Kazutoyo
AU - Nakamura, Haruna
AU - Sugiura, Katsumi
AU - Umemoto, Masakazu
AU - Kuroki, Haruo
AU - Ito, Hiroaki
AU - Tanaka, Shigeki
AU - Ito, Mitsue
AU - Fukuda, Saori
AU - Hatazawa, Riona
AU - Hara, Yuya
AU - Guntapong, Ratigorn
AU - Murata, Takayuki
AU - Taniguchi, Kiyosu
AU - Suga, Shigeru
AU - Nakano, Takashi
AU - Taniguchi, Koki
AU - Komoto, Satoshi
N1 - Publisher Copyright:
© 2019, National Institute of Health. All rights reserved.
PY - 2019
Y1 - 2019
N2 - The emergence of unusual DS-1-like intergenogroup reassortant rotaviruses with a bovinelike G8 genotype (DS-1-like G8P[8] strains) has been reported in several Asian countries. During the rotavirus surveillance program in Japan in 2017, a DS-1-like G8P[8] strain (RVA/Human-wt/JPN/ SO1162/2017/G8P[8]) was identified in 43 rotavirus-positive stool samples. Strain SO1162 was shown to have a unique genotype constellation, including genes from both genogroup 1 and 2: G8-P[8]-I2-R2- C2-M2-A2-N2-T2-E2-H2. Phylogenetic analysis revealed that the VP1 gene of strain SO1162 appeared to have originated from DS-1-like G1P[8] strains from Thailand and Vietnam, while the remaining 10 genes were closely related to those of previously reported DS-1-like G8P[8] strains. Thus, SO1162 was suggested to be a reassortant strain that acquired the VP1 gene from Southeast Asian DS-1-like G1P[8] strains on the genetic background of co-circulating DS-1-like G8P[8] strains. Our findings provide important insights into the evolutionary dynamics of emerging DS-1-like G8P[8] strains.
AB - The emergence of unusual DS-1-like intergenogroup reassortant rotaviruses with a bovinelike G8 genotype (DS-1-like G8P[8] strains) has been reported in several Asian countries. During the rotavirus surveillance program in Japan in 2017, a DS-1-like G8P[8] strain (RVA/Human-wt/JPN/ SO1162/2017/G8P[8]) was identified in 43 rotavirus-positive stool samples. Strain SO1162 was shown to have a unique genotype constellation, including genes from both genogroup 1 and 2: G8-P[8]-I2-R2- C2-M2-A2-N2-T2-E2-H2. Phylogenetic analysis revealed that the VP1 gene of strain SO1162 appeared to have originated from DS-1-like G1P[8] strains from Thailand and Vietnam, while the remaining 10 genes were closely related to those of previously reported DS-1-like G8P[8] strains. Thus, SO1162 was suggested to be a reassortant strain that acquired the VP1 gene from Southeast Asian DS-1-like G1P[8] strains on the genetic background of co-circulating DS-1-like G8P[8] strains. Our findings provide important insights into the evolutionary dynamics of emerging DS-1-like G8P[8] strains.
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U2 - 10.7883/yoken.JJID.2018.484
DO - 10.7883/yoken.JJID.2018.484
M3 - Article
C2 - 30814461
AN - SCOPUS:85070516875
SN - 1344-6304
VL - 72
SP - 256
EP - 260
JO - Japanese journal of infectious diseases
JF - Japanese journal of infectious diseases
IS - 4
ER -