TY - JOUR
T1 - Characterization of blaCTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings
AU - Matsuo, Nao
AU - Nonogaki, Rina
AU - Hayashi, Michiko
AU - Wachino, Jun Ichi
AU - Suzuki, Masahiro
AU - Arakawa, Yoshichika
AU - Kawamura, Kumiko
N1 - Funding Information:
This study was supported by the Research Program of the Health Labor Sciences Research grant H27-Iryo-Ippan-012. The plasmid sequencing was partially supported by AMED under grant 18jk0210004h0001.
Publisher Copyright:
© 2020 American Society for Microbiology.
PY - 2020/5
Y1 - 2020/5
N2 - We characterized 29 blaCTX-M-27-harboring plasmids of Escherichia coli sequence type 131 (ST131) sublineage C1/H30R isolates from healthy individuals and long-term-care facility (LTCF) residents. Most (27/29) plasmids were of the FIA, FIB, and FII multireplicon type with the same plasmid multilocus sequence typing (pMLST). Several plasmids (7/23) from LTCF residents harbored only blaCTX-M-27 as the resistance gene; however, their fundamental structures were very similar to those of previously isolated blaCTX-M-27/F1:A2:B20 plasmids, suggesting their prevalence as a newly arising public health concern.
AB - We characterized 29 blaCTX-M-27-harboring plasmids of Escherichia coli sequence type 131 (ST131) sublineage C1/H30R isolates from healthy individuals and long-term-care facility (LTCF) residents. Most (27/29) plasmids were of the FIA, FIB, and FII multireplicon type with the same plasmid multilocus sequence typing (pMLST). Several plasmids (7/23) from LTCF residents harbored only blaCTX-M-27 as the resistance gene; however, their fundamental structures were very similar to those of previously isolated blaCTX-M-27/F1:A2:B20 plasmids, suggesting their prevalence as a newly arising public health concern.
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U2 - 10.1128/AAC.00202-20
DO - 10.1128/AAC.00202-20
M3 - Article
C2 - 32152084
AN - SCOPUS:85083739368
VL - 64
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 5
M1 - e00202-20
ER -