Characterization of blaCTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings

Nao Matsuo; Rina Nonogaki; Michiko Hayashi; Jun Ichi Wachino; Masahiro Suzuki; Yoshichika Arakawa; Kumiko Kawamura

doi:10.1128/AAC.00202-20

Characterization of bla_CTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings

Nao Matsuo
, Rina Nonogaki
, Michiko Hayashi
, Jun Ichi Wachino
, Masahiro Suzuki
, Yoshichika Arakawa
, Kumiko Kawamura

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

We characterized 29 bla_CTX-M-27-harboring plasmids of Escherichia coli sequence type 131 (ST131) sublineage C1/H30R isolates from healthy individuals and long-term-care facility (LTCF) residents. Most (27/29) plasmids were of the FIA, FIB, and FII multireplicon type with the same plasmid multilocus sequence typing (pMLST). Several plasmids (7/23) from LTCF residents harbored only bla_CTX-M-27 as the resistance gene; however, their fundamental structures were very similar to those of previously isolated bla_CTX-M-27/F1:A2:B20 plasmids, suggesting their prevalence as a newly arising public health concern.

Original language	English
Article number	e00202-20
Journal	Antimicrobial agents and chemotherapy
Volume	64
Issue number	5
DOIs	https://doi.org/10.1128/AAC.00202-20
Publication status	Published - 05-2020
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1128/AAC.00202-20

Cite this

Matsuo, N., Nonogaki, R., Hayashi, M., Wachino, J. I., Suzuki, M., Arakawa, Y., & Kawamura, K. (2020). Characterization of bla_CTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings. Antimicrobial agents and chemotherapy, 64(5), Article e00202-20. https://doi.org/10.1128/AAC.00202-20

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title = "Characterization of blaCTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings",

abstract = "We characterized 29 blaCTX-M-27-harboring plasmids of Escherichia coli sequence type 131 (ST131) sublineage C1/H30R isolates from healthy individuals and long-term-care facility (LTCF) residents. Most (27/29) plasmids were of the FIA, FIB, and FII multireplicon type with the same plasmid multilocus sequence typing (pMLST). Several plasmids (7/23) from LTCF residents harbored only blaCTX-M-27 as the resistance gene; however, their fundamental structures were very similar to those of previously isolated blaCTX-M-27/F1:A2:B20 plasmids, suggesting their prevalence as a newly arising public health concern.",

keywords = "Bla, Elderly people, F1:A2:B20 plasmid, Next-generation sequencing analysis",

author = "Nao Matsuo and Rina Nonogaki and Michiko Hayashi and Wachino, \{Jun Ichi\} and Masahiro Suzuki and Yoshichika Arakawa and Kumiko Kawamura",

note = "Publisher Copyright: {\textcopyright} 2020 American Society for Microbiology.",

year = "2020",

month = may,

doi = "10.1128/AAC.00202-20",

language = "English",

volume = "64",

journal = "Antimicrobial agents and chemotherapy",

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Matsuo, N, Nonogaki, R, Hayashi, M, Wachino, JI , Suzuki, M , Arakawa, Y & Kawamura, K 2020, 'Characterization of bla_CTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings', Antimicrobial agents and chemotherapy, vol. 64, no. 5, e00202-20. https://doi.org/10.1128/AAC.00202-20

Characterization of bla_CTX-M-27/F1:A2:b20 plasmids harbored by escherichia coli sequence type 131 sublineage C1/H30R isolates spreading among elderly japanese in nonacute-care settings. / Matsuo, Nao; Nonogaki, Rina; Hayashi, Michiko et al.
In: Antimicrobial agents and chemotherapy, Vol. 64, No. 5, e00202-20, 05.2020.

Research output: Contribution to journal › Article › peer-review

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AU - Matsuo, Nao

AU - Nonogaki, Rina

AU - Hayashi, Michiko

AU - Wachino, Jun Ichi

AU - Suzuki, Masahiro

AU - Arakawa, Yoshichika

AU - Kawamura, Kumiko

PY - 2020/5

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AB - We characterized 29 blaCTX-M-27-harboring plasmids of Escherichia coli sequence type 131 (ST131) sublineage C1/H30R isolates from healthy individuals and long-term-care facility (LTCF) residents. Most (27/29) plasmids were of the FIA, FIB, and FII multireplicon type with the same plasmid multilocus sequence typing (pMLST). Several plasmids (7/23) from LTCF residents harbored only blaCTX-M-27 as the resistance gene; however, their fundamental structures were very similar to those of previously isolated blaCTX-M-27/F1:A2:B20 plasmids, suggesting their prevalence as a newly arising public health concern.

KW - Bla

KW - Elderly people

KW - F1:A2:B20 plasmid

KW - Next-generation sequencing analysis

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