Characterization of ventricular myocardial performance in the fetus by tissue Doppler imaging

Sayaka Watanabe; Ikuo Hashimoto; Kazuyoshi Saito; Kazuhiro Watanabe; Keiichi Hirono; Keiichiro Uese; Fukiko Ichida; Shigeru Saito; Toshio Miyawaki; Petra Niemann; David J. Sahn

doi:10.1253/circj.CJ-08-0529

Characterization of ventricular myocardial performance in the fetus by tissue Doppler imaging

Sayaka Watanabe, Ikuo Hashimoto, Kazuyoshi Saito, Kazuhiro Watanabe, Keiichi Hirono, Keiichiro Uese, Fukiko Ichida, Shigeru Saito, Toshio Miyawaki, Petra Niemann, David J. Sahn

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Background: Clinically useful indices of fetal cardiac function have not been fully delineated for tissue Doppler imaging (TDI). Methods and Results: In the present study, 56 pregnancies between the 17^th and 38 ^th weeks of gestation included 38 normal fetuses, 6 cases of hydrops fetalis (HF), and 12 of intrauterine growth retardation (IUGR). Peak velocity in early diastole (E) was measured by pulsed-wave Doppler and the peak annular velocities in systole (Sa) and early diastole (Ea) were measured by TDI. The ratio between flow velocity and annular velocity in early diastole (E/Ea) and the ratio of the Sa of right ventricle to that of the left ventricle (RVSa/LVSa) were estimated. In all fetuses with HF, LVSa was <2 cm/s and LVE/Ea was >13. RVSa/LVSa in the HF group was significantly higher than that in the normal group, and RVSa/LVSa in the IUGR group was significantly lower than that in the normal group. Conclusions: A combination of low LVSa and high LVE/Ea shows reduced global myocardial performance of the LV, and would be one of the useful indices for quantitative assessment in high-risk pregnancies. Changes in the RVSa/LVSa ratio may reflect afterload changes in both ventricles and compensatory cardiovascular mechanisms occurring during the process of placental insufficiency and heart failure.

Original language	English
Pages (from-to)	943-947
Number of pages	5
Journal	Circulation Journal
Volume	73
Issue number	5
DOIs	https://doi.org/10.1253/circj.CJ-08-0529
Publication status	Published - 05-2009
Externally published	Yes

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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10.1253/circj.CJ-08-0529

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title = "Characterization of ventricular myocardial performance in the fetus by tissue Doppler imaging",

abstract = "Background: Clinically useful indices of fetal cardiac function have not been fully delineated for tissue Doppler imaging (TDI). Methods and Results: In the present study, 56 pregnancies between the 17th and 38 th weeks of gestation included 38 normal fetuses, 6 cases of hydrops fetalis (HF), and 12 of intrauterine growth retardation (IUGR). Peak velocity in early diastole (E) was measured by pulsed-wave Doppler and the peak annular velocities in systole (Sa) and early diastole (Ea) were measured by TDI. The ratio between flow velocity and annular velocity in early diastole (E/Ea) and the ratio of the Sa of right ventricle to that of the left ventricle (RVSa/LVSa) were estimated. In all fetuses with HF, LVSa was <2 cm/s and LVE/Ea was >13. RVSa/LVSa in the HF group was significantly higher than that in the normal group, and RVSa/LVSa in the IUGR group was significantly lower than that in the normal group. Conclusions: A combination of low LVSa and high LVE/Ea shows reduced global myocardial performance of the LV, and would be one of the useful indices for quantitative assessment in high-risk pregnancies. Changes in the RVSa/LVSa ratio may reflect afterload changes in both ventricles and compensatory cardiovascular mechanisms occurring during the process of placental insufficiency and heart failure.",

author = "Sayaka Watanabe and Ikuo Hashimoto and Kazuyoshi Saito and Kazuhiro Watanabe and Keiichi Hirono and Keiichiro Uese and Fukiko Ichida and Shigeru Saito and Toshio Miyawaki and Petra Niemann and Sahn, {David J.}",

year = "2009",

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doi = "10.1253/circj.CJ-08-0529",

language = "English",

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T1 - Characterization of ventricular myocardial performance in the fetus by tissue Doppler imaging

AU - Watanabe, Sayaka

AU - Hashimoto, Ikuo

AU - Saito, Kazuyoshi

AU - Watanabe, Kazuhiro

AU - Hirono, Keiichi

AU - Uese, Keiichiro

AU - Ichida, Fukiko

AU - Saito, Shigeru

AU - Miyawaki, Toshio

AU - Niemann, Petra

AU - Sahn, David J.

PY - 2009/5

Y1 - 2009/5

N2 - Background: Clinically useful indices of fetal cardiac function have not been fully delineated for tissue Doppler imaging (TDI). Methods and Results: In the present study, 56 pregnancies between the 17th and 38 th weeks of gestation included 38 normal fetuses, 6 cases of hydrops fetalis (HF), and 12 of intrauterine growth retardation (IUGR). Peak velocity in early diastole (E) was measured by pulsed-wave Doppler and the peak annular velocities in systole (Sa) and early diastole (Ea) were measured by TDI. The ratio between flow velocity and annular velocity in early diastole (E/Ea) and the ratio of the Sa of right ventricle to that of the left ventricle (RVSa/LVSa) were estimated. In all fetuses with HF, LVSa was <2 cm/s and LVE/Ea was >13. RVSa/LVSa in the HF group was significantly higher than that in the normal group, and RVSa/LVSa in the IUGR group was significantly lower than that in the normal group. Conclusions: A combination of low LVSa and high LVE/Ea shows reduced global myocardial performance of the LV, and would be one of the useful indices for quantitative assessment in high-risk pregnancies. Changes in the RVSa/LVSa ratio may reflect afterload changes in both ventricles and compensatory cardiovascular mechanisms occurring during the process of placental insufficiency and heart failure.

AB - Background: Clinically useful indices of fetal cardiac function have not been fully delineated for tissue Doppler imaging (TDI). Methods and Results: In the present study, 56 pregnancies between the 17th and 38 th weeks of gestation included 38 normal fetuses, 6 cases of hydrops fetalis (HF), and 12 of intrauterine growth retardation (IUGR). Peak velocity in early diastole (E) was measured by pulsed-wave Doppler and the peak annular velocities in systole (Sa) and early diastole (Ea) were measured by TDI. The ratio between flow velocity and annular velocity in early diastole (E/Ea) and the ratio of the Sa of right ventricle to that of the left ventricle (RVSa/LVSa) were estimated. In all fetuses with HF, LVSa was <2 cm/s and LVE/Ea was >13. RVSa/LVSa in the HF group was significantly higher than that in the normal group, and RVSa/LVSa in the IUGR group was significantly lower than that in the normal group. Conclusions: A combination of low LVSa and high LVE/Ea shows reduced global myocardial performance of the LV, and would be one of the useful indices for quantitative assessment in high-risk pregnancies. Changes in the RVSa/LVSa ratio may reflect afterload changes in both ventricles and compensatory cardiovascular mechanisms occurring during the process of placental insufficiency and heart failure.

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JO - Circulation Journal

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ER -

Characterization of ventricular myocardial performance in the fetus by tissue Doppler imaging

Abstract

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