Chemoradiotherapy followed by restorative proctocolectomy with partial intersphincteric resection for advanced rectal cancer associated with ulcerative colitis: Report of a case

Yasuhiro Inoue, Toshimitsu Araki, Yoshinaga Okugawa, Aya Kawamoto, Junichiro Hiro, Yuji Toiyama, Koji Tanaka, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The role of restorative proctocolectomy with ileal J-pouch anal anastomosis (IPAA) is uncertain for patients with ulcerative colitis (UC), when advanced lower rectal cancer is diagnosed. We report what to our knowledge is the first documented case of successful preoperative chemoradiotherapy followed by IPAA with partial intersphincteric resection of advanced rectal cancer associated with UC. A 59-year-old woman with a 24-year history of extensive UC was found to have advanced rectal cancer located 2 cm from the anal verge. She underwent preoperative conventional chemoradiotherapy followed by restorative proctocolectomy with total mesorectal excision. The procedure included intersphincteric resection of one quadrant and construction of an IPAA with diverting ileostomy. The postoperative course was uneventful, and the ileostomy was closed 6 months after the initial surgery. The patient was doing well with good pouch function and no evidence of recurrent disease 1 year after her initial surgery.

Original languageEnglish
Pages (from-to)387-390
Number of pages4
JournalSurgery Today
Volume44
Issue number2
DOIs
Publication statusPublished - 02-2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery

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