Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

Mikio Hirayama; Tadanori Hamano; Masayuki Shiratori; Tatsuro Mutoh; Takanori Kumano; Takashi Aita; Masaru Kuriyama

doi:10.1016/S0022-510X(97)00072-5

Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

Mikio Hirayama
, Tadanori Hamano
, Masayuki Shiratori
, Tatsuro Mutoh
, Takanori Kumano
, Takashi Aita
, Masaru Kuriyama

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.

Original language	English
Pages (from-to)	23-24
Number of pages	2
Journal	Journal of the Neurological Sciences
Volume	151
Issue number	1
DOIs	https://doi.org/10.1016/S0022-510X(97)00072-5
Publication status	Published - 03-10-1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Neurology
Clinical Neurology

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10.1016/S0022-510X(97)00072-5

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abstract = "A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.",

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AU - Hirayama, Mikio

AU - Hamano, Tadanori

AU - Shiratori, Masayuki

AU - Mutoh, Tatsuro

AU - Kumano, Takanori

AU - Aita, Takashi

AU - Kuriyama, Masaru

PY - 1997/10/3

Y1 - 1997/10/3

N2 - A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.

AB - A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.

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UR - https://www.scopus.com/pages/publications/0030982462#tab=citedBy

U2 - 10.1016/S0022-510X(97)00072-5

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JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

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ER -

Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

Abstract

All Science Journal Classification (ASJC) codes

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