Chromosomal 16S Ribosomal RNA methyltransferase RmtE1 in Escherichia coli sequence type 448

Bin Li, Marissa P. Pacey, Yohei Doi

Research output: Contribution to journalLetter

1 Citation (Scopus)

Abstract

We identified rmtE1, an uncommon 16S ribosomal methyltransferase gene, in an aminoglycoside- and cephalosporin-resistant Escherichia coli sequence type 448 clinical strain co-harboring blaCMY-2. Long-read sequencing revealed insertion of a 101,257-bp fragment carrying both resistance genes to the chromosome. Our findings underscore E. coli sequence type 448 as a potential high-risk multidrug-resistant clone.

Original languageEnglish
Pages (from-to)876-878
Number of pages3
JournalEmerging Infectious Diseases
Volume23
Issue number5
DOIs
Publication statusPublished - 01-05-2017
Externally publishedYes

Fingerprint

16S Ribosomal RNA
Methyltransferases
Escherichia coli
Aminoglycosides
Cephalosporins
Genes
Clone Cells
Chromosomes

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

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abstract = "We identified rmtE1, an uncommon 16S ribosomal methyltransferase gene, in an aminoglycoside- and cephalosporin-resistant Escherichia coli sequence type 448 clinical strain co-harboring blaCMY-2. Long-read sequencing revealed insertion of a 101,257-bp fragment carrying both resistance genes to the chromosome. Our findings underscore E. coli sequence type 448 as a potential high-risk multidrug-resistant clone.",
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Chromosomal 16S Ribosomal RNA methyltransferase RmtE1 in Escherichia coli sequence type 448. / Li, Bin; Pacey, Marissa P.; Doi, Yohei.

In: Emerging Infectious Diseases, Vol. 23, No. 5, 01.05.2017, p. 876-878.

Research output: Contribution to journalLetter

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T1 - Chromosomal 16S Ribosomal RNA methyltransferase RmtE1 in Escherichia coli sequence type 448

AU - Li, Bin

AU - Pacey, Marissa P.

AU - Doi, Yohei

PY - 2017/5/1

Y1 - 2017/5/1

N2 - We identified rmtE1, an uncommon 16S ribosomal methyltransferase gene, in an aminoglycoside- and cephalosporin-resistant Escherichia coli sequence type 448 clinical strain co-harboring blaCMY-2. Long-read sequencing revealed insertion of a 101,257-bp fragment carrying both resistance genes to the chromosome. Our findings underscore E. coli sequence type 448 as a potential high-risk multidrug-resistant clone.

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