TY - JOUR
T1 - Chronic Kidney Disease and Coronary Artery Disease
T2 - JACC State-of-the-Art Review
AU - Conference Participants
AU - Sarnak, Mark J.
AU - Amann, Kerstin
AU - Bangalore, Sripal
AU - Cavalcante, João L.
AU - Charytan, David M.
AU - Craig, Jonathan C.
AU - Gill, John S.
AU - Hlatky, Mark A.
AU - Jardine, Alan G.
AU - Landmesser, Ulf
AU - Newby, L. Kristin
AU - Herzog, Charles A.
AU - Cheung, Michael
AU - Wheeler, David C.
AU - Winkelmayer, Wolfgang C.
AU - Marwick, Thomas H.
AU - Banerjee, Debasish
AU - Briguori, Carlo
AU - Chang, Tara I.
AU - Chen, Chien Liang
AU - deFilippi, Christopher R.
AU - Ding, Xiaoqiang
AU - Ferro, Charles J.
AU - Gill, Jagbir
AU - Gössl, Mario
AU - Isbel, Nicole M.
AU - Ishii, Hideki
AU - Jardine, Meg J.
AU - Kalra, Philip A.
AU - Laufer, Günther
AU - Lentine, Krista L.
AU - Lobdell, Kevin
AU - Lok, Charmaine E.
AU - London, Gérard M.
AU - Małyszko, Jolanta
AU - Mark, Patrick B.
AU - Marwan, Mohamed
AU - Nie, Yuxin
AU - Parfrey, Patrick S.
AU - Pecoits-Filho, Roberto
AU - Pilmore, Helen
AU - Qunibi, Wajeh Y.
AU - Raggi, Paolo
AU - Rattazzi, Marcello
AU - Rossignol, Patrick
AU - Ruturi, Josiah
AU - Sabanayagam, Charumathi
AU - Shanahan, Catherine M.
AU - Shroff, Gautam R.
AU - Shroff, Rukshana
N1 - Publisher Copyright:
© 2019 The Authors
PY - 2019/10/8
Y1 - 2019/10/8
N2 - Chronic kidney disease (CKD) is a major risk factor for coronary artery disease (CAD). As well as their high prevalence of traditional CAD risk factors, such as diabetes and hypertension, persons with CKD are also exposed to other nontraditional, uremia-related cardiovascular disease risk factors, including inflammation, oxidative stress, and abnormal calcium-phosphorus metabolism. CKD and end-stage kidney disease not only increase the risk of CAD, but they also modify its clinical presentation and cardinal symptoms. Management of CAD is complicated in CKD patients, due to their likelihood of comorbid conditions and potential for side effects during interventions. This summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference on CAD and CKD (including end-stage kidney disease and transplant recipients) seeks to improve understanding of the epidemiology, pathophysiology, diagnosis, and treatment of CAD in CKD and to identify knowledge gaps, areas of controversy, and priorities for research.
AB - Chronic kidney disease (CKD) is a major risk factor for coronary artery disease (CAD). As well as their high prevalence of traditional CAD risk factors, such as diabetes and hypertension, persons with CKD are also exposed to other nontraditional, uremia-related cardiovascular disease risk factors, including inflammation, oxidative stress, and abnormal calcium-phosphorus metabolism. CKD and end-stage kidney disease not only increase the risk of CAD, but they also modify its clinical presentation and cardinal symptoms. Management of CAD is complicated in CKD patients, due to their likelihood of comorbid conditions and potential for side effects during interventions. This summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference on CAD and CKD (including end-stage kidney disease and transplant recipients) seeks to improve understanding of the epidemiology, pathophysiology, diagnosis, and treatment of CAD in CKD and to identify knowledge gaps, areas of controversy, and priorities for research.
KW - acute coronary syndromes
KW - calcification
KW - chronic kidney disease
KW - coronary artery disease
KW - revascularization
UR - http://www.scopus.com/inward/record.url?scp=85072526119&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072526119&partnerID=8YFLogxK
U2 - 10.1016/j.jacc.2019.08.1017
DO - 10.1016/j.jacc.2019.08.1017
M3 - Review article
C2 - 31582143
AN - SCOPUS:85072526119
SN - 0735-1097
VL - 74
SP - 1823
EP - 1838
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 14
ER -
