Abstract
We report here a very rare case of chronic myeloid leukemia (CML) following long-term chemotherapy with 5′-deoxy-5-fluorouridine (5′-DFUR) for gastric cancer. A 69-year-old man was diagnosed with the chronic phase of CML. Six years previously, he underwent radical subtotal gastrectomy for gastric cancer, and was subsequently treated with oral anti-metabolite 5′-DFUR as adjuvant chemotherapy for 6 years. He was placed on imatinib therapy, and achieved a major molecular response 10 months after the initiation of therapy. This is the first reported case of therapy-related CML following 5′-DFUR treatment.
Original language | English |
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Pages (from-to) | 1739-1741 |
Number of pages | 3 |
Journal | Internal Medicine |
Volume | 47 |
Issue number | 19 |
DOIs | |
Publication status | Published - 2008 |
All Science Journal Classification (ASJC) codes
- Internal Medicine