Abstract
Background: Several epidermiologic studies reported the positive association between cigarette smoking and stomach cancer. The prevalence of smoking in men remains high in Japan compared to other developed countries. It is therefore of great importance to determine the impact of cigarette smoking on stomach cancer among the Japanese population. The Japan Collaborative Cohort Study (JACC Study) provided an opportunity to examine the association between smoking and the risk of mortality due to stomach cancer. Method: A baseline survey was conducted throughout Japan from 1988 through 1990 among 110,792 inhabitants of 45 areas. Data retrieved for 98,062 participants (43,482 male and 54,580 female) who provided sufficient information about their smoking habits, without any history of caner at the baseline. Of total 970,251 person-years, 757deaths due to stomach caner were identified. Results: Current smokers were at a higher risk of death due to stomach cancer than non-smokers (Hazard ratio = 1.36; 95% confidence interval [Cl]: 1.07, 1.73). The risk of, stomach cancer for men who smoked 15 or more cigarettes per day was approximately 1.4-fold greater than that of non-smokers, and those who smoked 35 or more cigarettes per day had an approximately 1.7-fold higher risk of stomach cancer, although the dose-response trend among men was unclear (p for trend = 0.063). No associations between smoking and stomach cancer were detected among women. Conclusion: The present results, together with previous findings, strongly support a hypothesis that cigarette smoking increases the risk of stomach cancer in Japanese men.
| Original language | English |
|---|---|
| Journal | Journal of epidemiology |
| Volume | 15 |
| Issue number | SUPPL. 2 |
| DOIs | |
| Publication status | Published - 14-10-2005 |
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All Science Journal Classification (ASJC) codes
- Epidemiology
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Cigarette smoking and mortality due to stomach cancer : Findings from the JACC study. / Fujino, Yoshihisa; Mizoue, Tetsuya; Tokui, Noritaka; Kikuchi, Shogo; Hoshiyama, Yoshihiro; Toyoshima, Hideaki; Yatsuya, Hiroshi; Sakata, Kiyomi; Tamakoshi, Akiko; Ide, Reiko; Kubo, Tatsuhiko; Yoshimura, Takesumi; Mori, Mitsuru; Motohashi, Yutaka; Tsuji, Ichiro; Nakamura, Yosikazu; Iso, Hiroyasu; Mikami, Haruo; Inaba, Yutaka; Hoshiyama, Yoshiharu; Suzuki, Hiroshi; Shimizu, Hiroyuki; Wakai, Kenji; Tokudome, Shinkan; Ito, Yoshinori; Hashimoto, Shuji; Koizumi, Akio; Kawamura, Takashi; Watanabe, Yoshiyuki; Miki, Tsuneharu; Date, Chigusa; Nose, Takayuki; Hayakawa, Norihiko; Shibata, Akira; Okamoto, Naoyuki; Shio, Hideo; Ohno, Yoshiyuki; Kitagawa, Tomoyuki; Kuroki, Toshio; Tajima, Kazuo.
In: Journal of epidemiology, Vol. 15, No. SUPPL. 2, 14.10.2005.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cigarette smoking and mortality due to stomach cancer
T2 - Findings from the JACC study
AU - Fujino, Yoshihisa
AU - Mizoue, Tetsuya
AU - Tokui, Noritaka
AU - Kikuchi, Shogo
AU - Hoshiyama, Yoshihiro
AU - Toyoshima, Hideaki
AU - Yatsuya, Hiroshi
AU - Sakata, Kiyomi
AU - Tamakoshi, Akiko
AU - Ide, Reiko
AU - Kubo, Tatsuhiko
AU - Yoshimura, Takesumi
AU - Mori, Mitsuru
AU - Motohashi, Yutaka
AU - Tsuji, Ichiro
AU - Nakamura, Yosikazu
AU - Iso, Hiroyasu
AU - Mikami, Haruo
AU - Inaba, Yutaka
AU - Hoshiyama, Yoshiharu
AU - Suzuki, Hiroshi
AU - Shimizu, Hiroyuki
AU - Wakai, Kenji
AU - Tokudome, Shinkan
AU - Ito, Yoshinori
AU - Hashimoto, Shuji
AU - Koizumi, Akio
AU - Kawamura, Takashi
AU - Watanabe, Yoshiyuki
AU - Miki, Tsuneharu
AU - Date, Chigusa
AU - Nose, Takayuki
AU - Hayakawa, Norihiko
AU - Shibata, Akira
AU - Okamoto, Naoyuki
AU - Shio, Hideo
AU - Ohno, Yoshiyuki
AU - Kitagawa, Tomoyuki
AU - Kuroki, Toshio
AU - Tajima, Kazuo
PY - 2005/10/14
Y1 - 2005/10/14
N2 - Background: Several epidermiologic studies reported the positive association between cigarette smoking and stomach cancer. The prevalence of smoking in men remains high in Japan compared to other developed countries. It is therefore of great importance to determine the impact of cigarette smoking on stomach cancer among the Japanese population. The Japan Collaborative Cohort Study (JACC Study) provided an opportunity to examine the association between smoking and the risk of mortality due to stomach cancer. Method: A baseline survey was conducted throughout Japan from 1988 through 1990 among 110,792 inhabitants of 45 areas. Data retrieved for 98,062 participants (43,482 male and 54,580 female) who provided sufficient information about their smoking habits, without any history of caner at the baseline. Of total 970,251 person-years, 757deaths due to stomach caner were identified. Results: Current smokers were at a higher risk of death due to stomach cancer than non-smokers (Hazard ratio = 1.36; 95% confidence interval [Cl]: 1.07, 1.73). The risk of, stomach cancer for men who smoked 15 or more cigarettes per day was approximately 1.4-fold greater than that of non-smokers, and those who smoked 35 or more cigarettes per day had an approximately 1.7-fold higher risk of stomach cancer, although the dose-response trend among men was unclear (p for trend = 0.063). No associations between smoking and stomach cancer were detected among women. Conclusion: The present results, together with previous findings, strongly support a hypothesis that cigarette smoking increases the risk of stomach cancer in Japanese men.
AB - Background: Several epidermiologic studies reported the positive association between cigarette smoking and stomach cancer. The prevalence of smoking in men remains high in Japan compared to other developed countries. It is therefore of great importance to determine the impact of cigarette smoking on stomach cancer among the Japanese population. The Japan Collaborative Cohort Study (JACC Study) provided an opportunity to examine the association between smoking and the risk of mortality due to stomach cancer. Method: A baseline survey was conducted throughout Japan from 1988 through 1990 among 110,792 inhabitants of 45 areas. Data retrieved for 98,062 participants (43,482 male and 54,580 female) who provided sufficient information about their smoking habits, without any history of caner at the baseline. Of total 970,251 person-years, 757deaths due to stomach caner were identified. Results: Current smokers were at a higher risk of death due to stomach cancer than non-smokers (Hazard ratio = 1.36; 95% confidence interval [Cl]: 1.07, 1.73). The risk of, stomach cancer for men who smoked 15 or more cigarettes per day was approximately 1.4-fold greater than that of non-smokers, and those who smoked 35 or more cigarettes per day had an approximately 1.7-fold higher risk of stomach cancer, although the dose-response trend among men was unclear (p for trend = 0.063). No associations between smoking and stomach cancer were detected among women. Conclusion: The present results, together with previous findings, strongly support a hypothesis that cigarette smoking increases the risk of stomach cancer in Japanese men.
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UR - http://www.scopus.com/inward/citedby.url?scp=26244454991&partnerID=8YFLogxK
U2 - 10.2188/jea.15.S113
DO - 10.2188/jea.15.S113
M3 - Article
VL - 15
JO - Journal of Epidemiology
JF - Journal of Epidemiology
SN - 0917-5040
IS - SUPPL. 2
ER -