Clinical analysis of 35 cases of penile cancer

Taku Kato, Hidetoshi Ehara, Kimiaki Takagi, Kengo Horie, Shinichi Hattori, Keita Nakane, Kensaku Seike, Takashi Sugawara, Takahiro Goto, Naruyasu Masue, Masayoshi Tamaki, Yasuhisa Ito, Takashi Deguchi

Research output: Contribution to journalArticlepeer-review

Abstract

We retrospectively reviewed the records of 35 patients with penile cancer, who had been treated at Gifu University Hospital and its affiliated hospitals between July 1994 and January 2009. The mean values of follow-up periods, ages, serum squamous cell carcinoma levels and maximum diameters of the tumor were 23.7 ± 28.0 months, 72.3 ± 10.5 year-old, 4.5 ± 4.3 ng/ml, and 4.0 ± 2.6 cm, respectively. Systemic chemotherapy and local radiotherapy were performed in six, and three cases, respectively. Ten patients died of penile cancer. By univariate analyses, maximum tumor diameter (≤4.3 cm vs >4.3 cm), T factor (<T3 vs ≥T3) and N factor (<N2 vs ≥N2) were significantly associated with cancer-specific survival. The five-year survival of stage N2 cases (28.6%) were significantly lower than that of stage N0 and N1 cases (68.4%) (p= 0.0003). By multivariate analyses N factor (<N2 vs ≥N2) was significantly associated with cancer specific survival (p= 0.020). We concluded that the development of effective systemic chemotherapy might be crucial to improve the prognosis of patients with metastatic diseases.

Original languageEnglish
Pages (from-to)363-366
Number of pages4
JournalActa Urologica Japonica
Volume57
Issue number7
Publication statusPublished - 31-07-2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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