TY - JOUR
T1 - Clinical and oncological benefits of left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma
AU - Nakanishi, Yoshitsugu
AU - Hirano, Satoshi
AU - Okamura, Keisuke
AU - Tsuchikawa, Takahiro
AU - Nakamura, Toru
AU - Noji, Takehiro
AU - Asano, Toshimichi
AU - Matsui, Aya
AU - Tanaka, Kimitaka
AU - Murakami, Soichi
AU - Ebihara, Yuma
AU - Kurashima, Yo
AU - Watanabe, Yusuke
AU - Shichinohe, Toshiaki
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd.
PY - 2022/5
Y1 - 2022/5
N2 - Purpose: This retrospective study aimed to clarify whether the postoperative prognosis differs between right and left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma. Methods: Preoperative images of 195 patients with perihilar cholangiocarcinoma were reexamined. Patients with Bismuth type I/II perihilar cholangiocarcinoma without a difference in extraductal tumor invasion between the right and left sides of the hepatic portal region were classified into those undergoing left (L group) or right (R group) hepatectomy. Results: Twenty-three patients (11.8%) were classified into the L group and 33 (16.9%) into the R group. All eight patients with pTis/1 belonged to the L group. The L group had significantly less liver failure than the R group (p = 0.001). One patient (4.3%) in the L group and four patients (12.1%) in the R group died from postoperative complications. Among 48 patients with pT2, the L group tended to have better overall survival (median, 12.2 vs. 5.6 years; p = 0.072), but not recurrence-free survival (median, 9.1 vs. 3.6 years; p = 0.477), in comparison to the R group. Conclusions: Postoperative survival after left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma is expected to be as long as that after right hepatectomy.
AB - Purpose: This retrospective study aimed to clarify whether the postoperative prognosis differs between right and left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma. Methods: Preoperative images of 195 patients with perihilar cholangiocarcinoma were reexamined. Patients with Bismuth type I/II perihilar cholangiocarcinoma without a difference in extraductal tumor invasion between the right and left sides of the hepatic portal region were classified into those undergoing left (L group) or right (R group) hepatectomy. Results: Twenty-three patients (11.8%) were classified into the L group and 33 (16.9%) into the R group. All eight patients with pTis/1 belonged to the L group. The L group had significantly less liver failure than the R group (p = 0.001). One patient (4.3%) in the L group and four patients (12.1%) in the R group died from postoperative complications. Among 48 patients with pT2, the L group tended to have better overall survival (median, 12.2 vs. 5.6 years; p = 0.072), but not recurrence-free survival (median, 9.1 vs. 3.6 years; p = 0.477), in comparison to the R group. Conclusions: Postoperative survival after left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma is expected to be as long as that after right hepatectomy.
UR - https://www.scopus.com/pages/publications/85118300679
UR - https://www.scopus.com/pages/publications/85118300679#tab=citedBy
U2 - 10.1007/s00595-021-02401-7
DO - 10.1007/s00595-021-02401-7
M3 - Article
C2 - 34724106
AN - SCOPUS:85118300679
SN - 0941-1291
VL - 52
SP - 844
EP - 852
JO - Surgery Today
JF - Surgery Today
IS - 5
ER -