Clinical characteristics and risk factors of chronic subdural haematoma associated with clipping of unruptured cerebral aneurysms

Joji Inamasu, Takeya Watabe, Tsukasa Ganaha, Yasuhiro Yamada, Shunsuke Nakae, Tatsuo Ohmi, Shuei Imizu, Takafumi Kaito, Keisuke Ito, Yuya Nishiyama, Takuro Hayashi, Hirotoshi Sano, Yoko Kato, Yuichi Hirose

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Chronic subdural haematoma (CSDH) is an uncommon but potentially serious complication of clipping unruptured cerebral aneurysms. We conducted a study to identify the patients who are at risk of developing postoperative CSDH. The data from 713 consecutive patients who underwent clipping of unruptured anterior circulation aneurysms were reviewed, and risk factors correlated with CSDH were identified by multivariate regression analysis of demographic variables. Fifteen patients (2.1%) developed CSDH after the surgery. Advanced age (odds ratio [OR] 1.151, 95% confidence interval [CI] 1.051-1.261) and male gender (OR 3.167, 95% CI 1.028-9.751) were correlated with CSDH. Subsequently, all 713 patients were quadrichotomized on the basis of gender and age, with 70 years as the cut-off value for age. The frequency of CSDH in men <70 years of age was 1.3% and that in men ≥70 years of age was 15.1%, with risk of CSDH was significantly higher in the older men (OR 13.39; 95% CI: 3.42-52.44). The frequency of CSDH in women <70 years of age was 0.6% and that in women ≥70 years of age was 3.7%. As in men, the risk of CSDH was significantly higher in the older women (OR 6.69, 95% CI 1.10-40.73). The interval between the aneurysm clipping and CSDH development was 0.5-6 months, suggesting that clinical observation should be continued up to 6 months after surgery. Although prognosis for patients with a postoperative CSDH complication is generally favourable, the risk of CSDH should be taken into account when considering elective clipping of unruptured aneurysms in patients ≥70 years of age.

Original languageEnglish
Pages (from-to)1095-1098
Number of pages4
JournalJournal of Clinical Neuroscience
Volume20
Issue number8
DOIs
Publication statusPublished - 01-08-2013

Fingerprint

Hematoma, Subdural, Chronic
Intracranial Aneurysm
Odds Ratio
Confidence Intervals
Aneurysm

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Inamasu, Joji ; Watabe, Takeya ; Ganaha, Tsukasa ; Yamada, Yasuhiro ; Nakae, Shunsuke ; Ohmi, Tatsuo ; Imizu, Shuei ; Kaito, Takafumi ; Ito, Keisuke ; Nishiyama, Yuya ; Hayashi, Takuro ; Sano, Hirotoshi ; Kato, Yoko ; Hirose, Yuichi. / Clinical characteristics and risk factors of chronic subdural haematoma associated with clipping of unruptured cerebral aneurysms. In: Journal of Clinical Neuroscience. 2013 ; Vol. 20, No. 8. pp. 1095-1098.
@article{861a47ee2e3944ce856f9498cd39c216,
title = "Clinical characteristics and risk factors of chronic subdural haematoma associated with clipping of unruptured cerebral aneurysms",
abstract = "Chronic subdural haematoma (CSDH) is an uncommon but potentially serious complication of clipping unruptured cerebral aneurysms. We conducted a study to identify the patients who are at risk of developing postoperative CSDH. The data from 713 consecutive patients who underwent clipping of unruptured anterior circulation aneurysms were reviewed, and risk factors correlated with CSDH were identified by multivariate regression analysis of demographic variables. Fifteen patients (2.1{\%}) developed CSDH after the surgery. Advanced age (odds ratio [OR] 1.151, 95{\%} confidence interval [CI] 1.051-1.261) and male gender (OR 3.167, 95{\%} CI 1.028-9.751) were correlated with CSDH. Subsequently, all 713 patients were quadrichotomized on the basis of gender and age, with 70 years as the cut-off value for age. The frequency of CSDH in men <70 years of age was 1.3{\%} and that in men ≥70 years of age was 15.1{\%}, with risk of CSDH was significantly higher in the older men (OR 13.39; 95{\%} CI: 3.42-52.44). The frequency of CSDH in women <70 years of age was 0.6{\%} and that in women ≥70 years of age was 3.7{\%}. As in men, the risk of CSDH was significantly higher in the older women (OR 6.69, 95{\%} CI 1.10-40.73). The interval between the aneurysm clipping and CSDH development was 0.5-6 months, suggesting that clinical observation should be continued up to 6 months after surgery. Although prognosis for patients with a postoperative CSDH complication is generally favourable, the risk of CSDH should be taken into account when considering elective clipping of unruptured aneurysms in patients ≥70 years of age.",
author = "Joji Inamasu and Takeya Watabe and Tsukasa Ganaha and Yasuhiro Yamada and Shunsuke Nakae and Tatsuo Ohmi and Shuei Imizu and Takafumi Kaito and Keisuke Ito and Yuya Nishiyama and Takuro Hayashi and Hirotoshi Sano and Yoko Kato and Yuichi Hirose",
year = "2013",
month = "8",
day = "1",
doi = "10.1016/j.jocn.2012.09.024",
language = "English",
volume = "20",
pages = "1095--1098",
journal = "Journal of Clinical Neuroscience",
issn = "0967-5868",
publisher = "Churchill Livingstone",
number = "8",

}

Inamasu, J, Watabe, T, Ganaha, T, Yamada, Y, Nakae, S, Ohmi, T, Imizu, S, Kaito, T, Ito, K, Nishiyama, Y, Hayashi, T, Sano, H, Kato, Y & Hirose, Y 2013, 'Clinical characteristics and risk factors of chronic subdural haematoma associated with clipping of unruptured cerebral aneurysms', Journal of Clinical Neuroscience, vol. 20, no. 8, pp. 1095-1098. https://doi.org/10.1016/j.jocn.2012.09.024

Clinical characteristics and risk factors of chronic subdural haematoma associated with clipping of unruptured cerebral aneurysms. / Inamasu, Joji; Watabe, Takeya; Ganaha, Tsukasa; Yamada, Yasuhiro; Nakae, Shunsuke; Ohmi, Tatsuo; Imizu, Shuei; Kaito, Takafumi; Ito, Keisuke; Nishiyama, Yuya; Hayashi, Takuro; Sano, Hirotoshi; Kato, Yoko; Hirose, Yuichi.

In: Journal of Clinical Neuroscience, Vol. 20, No. 8, 01.08.2013, p. 1095-1098.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Clinical characteristics and risk factors of chronic subdural haematoma associated with clipping of unruptured cerebral aneurysms

AU - Inamasu, Joji

AU - Watabe, Takeya

AU - Ganaha, Tsukasa

AU - Yamada, Yasuhiro

AU - Nakae, Shunsuke

AU - Ohmi, Tatsuo

AU - Imizu, Shuei

AU - Kaito, Takafumi

AU - Ito, Keisuke

AU - Nishiyama, Yuya

AU - Hayashi, Takuro

AU - Sano, Hirotoshi

AU - Kato, Yoko

AU - Hirose, Yuichi

PY - 2013/8/1

Y1 - 2013/8/1

N2 - Chronic subdural haematoma (CSDH) is an uncommon but potentially serious complication of clipping unruptured cerebral aneurysms. We conducted a study to identify the patients who are at risk of developing postoperative CSDH. The data from 713 consecutive patients who underwent clipping of unruptured anterior circulation aneurysms were reviewed, and risk factors correlated with CSDH were identified by multivariate regression analysis of demographic variables. Fifteen patients (2.1%) developed CSDH after the surgery. Advanced age (odds ratio [OR] 1.151, 95% confidence interval [CI] 1.051-1.261) and male gender (OR 3.167, 95% CI 1.028-9.751) were correlated with CSDH. Subsequently, all 713 patients were quadrichotomized on the basis of gender and age, with 70 years as the cut-off value for age. The frequency of CSDH in men <70 years of age was 1.3% and that in men ≥70 years of age was 15.1%, with risk of CSDH was significantly higher in the older men (OR 13.39; 95% CI: 3.42-52.44). The frequency of CSDH in women <70 years of age was 0.6% and that in women ≥70 years of age was 3.7%. As in men, the risk of CSDH was significantly higher in the older women (OR 6.69, 95% CI 1.10-40.73). The interval between the aneurysm clipping and CSDH development was 0.5-6 months, suggesting that clinical observation should be continued up to 6 months after surgery. Although prognosis for patients with a postoperative CSDH complication is generally favourable, the risk of CSDH should be taken into account when considering elective clipping of unruptured aneurysms in patients ≥70 years of age.

AB - Chronic subdural haematoma (CSDH) is an uncommon but potentially serious complication of clipping unruptured cerebral aneurysms. We conducted a study to identify the patients who are at risk of developing postoperative CSDH. The data from 713 consecutive patients who underwent clipping of unruptured anterior circulation aneurysms were reviewed, and risk factors correlated with CSDH were identified by multivariate regression analysis of demographic variables. Fifteen patients (2.1%) developed CSDH after the surgery. Advanced age (odds ratio [OR] 1.151, 95% confidence interval [CI] 1.051-1.261) and male gender (OR 3.167, 95% CI 1.028-9.751) were correlated with CSDH. Subsequently, all 713 patients were quadrichotomized on the basis of gender and age, with 70 years as the cut-off value for age. The frequency of CSDH in men <70 years of age was 1.3% and that in men ≥70 years of age was 15.1%, with risk of CSDH was significantly higher in the older men (OR 13.39; 95% CI: 3.42-52.44). The frequency of CSDH in women <70 years of age was 0.6% and that in women ≥70 years of age was 3.7%. As in men, the risk of CSDH was significantly higher in the older women (OR 6.69, 95% CI 1.10-40.73). The interval between the aneurysm clipping and CSDH development was 0.5-6 months, suggesting that clinical observation should be continued up to 6 months after surgery. Although prognosis for patients with a postoperative CSDH complication is generally favourable, the risk of CSDH should be taken into account when considering elective clipping of unruptured aneurysms in patients ≥70 years of age.

UR - http://www.scopus.com/inward/record.url?scp=84879971571&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879971571&partnerID=8YFLogxK

U2 - 10.1016/j.jocn.2012.09.024

DO - 10.1016/j.jocn.2012.09.024

M3 - Article

C2 - 23669172

AN - SCOPUS:84879971571

VL - 20

SP - 1095

EP - 1098

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

SN - 0967-5868

IS - 8

ER -