Clinical efficacy of aerosol therapy for chronic sinusitis patients and basic study of aerosolized particle inflow into the maxillary sinus

Aerosol therapy is widely used to treat chronic sinusitis at ear, nose, and throat (ENT) clinics. Sending aerosolized particles efficiently to inflamed paranasal sinus mucosa is an important issue in this area. We compared the extent of aerosolized particle inflow into an adult artificial maxillary sinus (Koken Co., Ltd) using of 3 types of nebulizer——Nissho compressor A (jet nebulizer), Azwell Nescojet AZ-11 (jet nebulizer), and Azwell UN-701 (ultrasonic nebulizer). The greater the ostium size, the greater the aerosolized particle transfer to the maxillary sinus. The greatest inflow of aerosolized particles was by Nissho compressor-A. No significant difference in clinical efficacy for chronic sinusitis patients was seen in the 3 types of nebulizer.