Clinical evaluation of children's skin care products containing β-thujaplicin (Hinokitiol)

K. Yoshikawa, H. Ueda, K. Matsunaga, R. Hayakawa, M. Ueda

Research output: Contribution to journalArticlepeer-review


We evaluated the skin safety and usefulness of BS-1210 (Bean Stalk Series); Hair Shampoo and Skin Lotion, skin care products for children containing β-thujaplic (Hinokitiol), an antibacterial agent. Thirty-five infants and children under the age of 7 suffering from the following skin diseases; atopic dermatitis (29), dry form eczema infantum (3), infantile seborrheic dermatitis (2), and infantile dermatitis (1) were selected for this study. The hair shampoo was used every day or every other day during the bath. The skin lotion was applied simply twice a day. These products were used for 4 weeks according to the doctor's instructions, and the skin conditions were monitored at 2 weeks interval. The skin conditions of 26 (90%) out of 29 atopic dermatitis patients and all cases (100%) of other patients improved significantly on the final observation, while no apparent adverse reaction was seen. Accordingly, BS-1210 was evaluated as effective in 32 cases (91%). We concluded that the BS-1210 was a safe and useful formula for the skin care of the children and can also be used as a supplement for the treatment of atopic dermatitis or other skin diseases of the infants and the children.

Original languageEnglish
Pages (from-to)262-275
Number of pages14
Journalskin research
Issue number2
Publication statusPublished - 01-01-1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases


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