Clinical features of primary human herpesvirus-6 infection in an infant with acute lymphoblastic leukemia

T. Yoshikawa, I. Kobayashi, Y. Asano, T. Nakashima, T. Yazaki, S. Kojima, A. Yamada

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Purpose: The primary infection with human herpesvirus-6 developed concurrently with diagnosis of acute lymphoblastic leukemia and initiation of intensive chemotherapy for the disease in a 4-month-old girl. Results: Prolonged viremia persisted for 7 days in the presence of neutralizing antibodies, and clinical features such as prolonged febrile and diarrheal period, no appearance of skin rash, and marked bulging fontanelle for 7 days in the absence of the virus DNA in spinal fluid may suggest an atypical clinical course of exanthem subitum and an unusual viral replication in immunocompromised condition.

Original languageEnglish
Pages (from-to)424-426
Number of pages3
JournalAmerican Journal of Pediatric Hematology/Oncology
Volume15
Issue number4
Publication statusPublished - 1993

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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