Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction

Satoshi Isobe, Mitsuhiro Okada, Akitada Ando, Mamoru Nanasato, Makoto Nonokawa, Hideo Izawa, Takahisa Kondo, Makoto Hirai, Mitsuhiro Yokota, Yoshifumi Tanahashi, Hidehiko Saito

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-β-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (ΔEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the ΔEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r = .63, P < .001; r = .74, P < .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI.

Original languageEnglish
Pages (from-to)173-180
Number of pages8
JournalJournal of Electrocardiology
Volume35
Issue number3
DOIs
Publication statusPublished - 01-01-2002
Externally publishedYes

Fingerprint

Thallium
Thorax
Myocardial Infarction
Single-Photon Emission-Computed Tomography
Iodine
Stroke Volume
Echocardiography
Emergencies
iodofiltic acid

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Isobe, Satoshi ; Okada, Mitsuhiro ; Ando, Akitada ; Nanasato, Mamoru ; Nonokawa, Makoto ; Izawa, Hideo ; Kondo, Takahisa ; Hirai, Makoto ; Yokota, Mitsuhiro ; Tanahashi, Yoshifumi ; Saito, Hidehiko. / Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction. In: Journal of Electrocardiology. 2002 ; Vol. 35, No. 3. pp. 173-180.
@article{f345297c25db4d5184eae1189170bad8,
title = "Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction",
abstract = "This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-β-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [({\%}) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [({\%}) increase of R wave] and the increase of left ventricular ejection fraction (ΔEF) from 1 to 4 weeks were obtained. There were significant correlations between the ({\%}) increase of R wave and the ΔEF as well as between the ({\%}) increase of R wave and the ({\%}) discordance on TI/BMIPP (r = .63, P < .001; r = .74, P < .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI.",
author = "Satoshi Isobe and Mitsuhiro Okada and Akitada Ando and Mamoru Nanasato and Makoto Nonokawa and Hideo Izawa and Takahisa Kondo and Makoto Hirai and Mitsuhiro Yokota and Yoshifumi Tanahashi and Hidehiko Saito",
year = "2002",
month = "1",
day = "1",
doi = "10.1054/jelc.2002.33761",
language = "English",
volume = "35",
pages = "173--180",
journal = "Journal of Electrocardiology",
issn = "0022-0736",
publisher = "Churchill Livingstone",
number = "3",

}

Isobe, S, Okada, M, Ando, A, Nanasato, M, Nonokawa, M, Izawa, H, Kondo, T, Hirai, M, Yokota, M, Tanahashi, Y & Saito, H 2002, 'Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction', Journal of Electrocardiology, vol. 35, no. 3, pp. 173-180. https://doi.org/10.1054/jelc.2002.33761

Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction. / Isobe, Satoshi; Okada, Mitsuhiro; Ando, Akitada; Nanasato, Mamoru; Nonokawa, Makoto; Izawa, Hideo; Kondo, Takahisa; Hirai, Makoto; Yokota, Mitsuhiro; Tanahashi, Yoshifumi; Saito, Hidehiko.

In: Journal of Electrocardiology, Vol. 35, No. 3, 01.01.2002, p. 173-180.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction

AU - Isobe, Satoshi

AU - Okada, Mitsuhiro

AU - Ando, Akitada

AU - Nanasato, Mamoru

AU - Nonokawa, Makoto

AU - Izawa, Hideo

AU - Kondo, Takahisa

AU - Hirai, Makoto

AU - Yokota, Mitsuhiro

AU - Tanahashi, Yoshifumi

AU - Saito, Hidehiko

PY - 2002/1/1

Y1 - 2002/1/1

N2 - This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-β-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (ΔEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the ΔEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r = .63, P < .001; r = .74, P < .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI.

AB - This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-β-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (ΔEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the ΔEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r = .63, P < .001; r = .74, P < .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI.

UR - http://www.scopus.com/inward/record.url?scp=0036077178&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036077178&partnerID=8YFLogxK

U2 - 10.1054/jelc.2002.33761

DO - 10.1054/jelc.2002.33761

M3 - Article

VL - 35

SP - 173

EP - 180

JO - Journal of Electrocardiology

JF - Journal of Electrocardiology

SN - 0022-0736

IS - 3

ER -