TY - JOUR
T1 - Clinical significance of jejunoileal involvement of non-Hodgkin's lymphoma detected by double-balloon enteroscopy
AU - Ibuka, Takashi
AU - Tsurumi, Hisashi
AU - Araki, Hiroshi
AU - Hara, Takeshi
AU - Onogi, Fumito
AU - Goto, Naoe
AU - Kojima, Yasushi
AU - Kanemura, Nobuhiro
AU - Shiraki, Makoto
AU - Kasahara, Senji
AU - Shimizu, Masahito
AU - Ogawa, Kengo
AU - Ninomiya, Soranobu
AU - Nakanishi, Takayuki
AU - Kato, Tomohiro
AU - Takami, Tsuyoshi
AU - Moriwaki, Hisataka
PY - 2013/3
Y1 - 2013/3
N2 - Jejunoileal involvement of non-Hodgkin's lymphoma (NHL) is an important diagnostic factor in determining optimal treatment strategies. Here, we used double-balloon enteroscopy (DBE) to detect jejunoileal involvement of NHL and studied its clinical significance in a series of patients with NHL. Adults aged between 18 and 85 years with infiltration of the stomach, duodenum, or colon confirmed by gastrointestinal endoscopy or colonoscopy, suspected jejunoileal involvement determined by CT or FDG-PET, or any other gastrointestinal symptoms, were eligible for inclusion in the study. Among 428 patients with histologically confirmed NHL between 2004 and 2011, 83 were eligible for DBE, but 20 patients were excluded due to rejection or poor clinical status. Thus, 63 underwent DBE. The 3-year overall survival rate was significantly lower in patients with (n = 33), than without (n = 30) jejunoileal involvement of NHL confirmed by DBE (49 vs. 92 %, p<0.005). Four participants developed aspiration pneumonia, but recovered after treatment with antibiotics.
AB - Jejunoileal involvement of non-Hodgkin's lymphoma (NHL) is an important diagnostic factor in determining optimal treatment strategies. Here, we used double-balloon enteroscopy (DBE) to detect jejunoileal involvement of NHL and studied its clinical significance in a series of patients with NHL. Adults aged between 18 and 85 years with infiltration of the stomach, duodenum, or colon confirmed by gastrointestinal endoscopy or colonoscopy, suspected jejunoileal involvement determined by CT or FDG-PET, or any other gastrointestinal symptoms, were eligible for inclusion in the study. Among 428 patients with histologically confirmed NHL between 2004 and 2011, 83 were eligible for DBE, but 20 patients were excluded due to rejection or poor clinical status. Thus, 63 underwent DBE. The 3-year overall survival rate was significantly lower in patients with (n = 33), than without (n = 30) jejunoileal involvement of NHL confirmed by DBE (49 vs. 92 %, p<0.005). Four participants developed aspiration pneumonia, but recovered after treatment with antibiotics.
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U2 - 10.1007/s12185-013-1273-4
DO - 10.1007/s12185-013-1273-4
M3 - Article
C2 - 23378170
AN - SCOPUS:84887601928
VL - 97
SP - 369
EP - 381
JO - International Journal of Hematology
JF - International Journal of Hematology
SN - 0925-5710
IS - 3
ER -