Clinical studies of FK037 on complicated urinary tract infection

Keizo Suzuki, Masaki Horiba, Shinobu Katoh, Masahiro Yonezu, Kiyohito Ishikawa, Yorio Naide, Masanori Yanaoka, Shinichi Ando

Research output: Contribution to journalArticlepeer-review

Abstract

FK037, a new injectable cephem antibiotic, was administered in the treatment of 14 complicated urinary tract infections. The drug was given at doses of 0.25~1.0g b. i. d. by intravenous drip infusion for 5 days. The clinical efficacy was evaluated as excellent or moderate in 11 cases out of 13, 85% by the Japanese UTI criteria. Bacteriologically, 20 strains out of 22, 91% were eradicated after the therapy. Against strains of Pseudomonas aeruginosa, the response was 1 out of 3 strains. In the safety profile, no side events or abnormal laboratory findings were caused by FK037.

Original languageEnglish
Pages (from-to)448-453
Number of pages6
JournalCHEMOTHERAPY
Volume42
DOIs
Publication statusPublished - 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Infectious Diseases
  • Pharmacology
  • Drug Discovery
  • Oncology

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