FK037, a new injectable cephem antibiotic, was administered in the treatment of 14 complicated urinary tract infections. The drug was given at doses of 0.25~1.0g b. i. d. by intravenous drip infusion for 5 days. The clinical efficacy was evaluated as excellent or moderate in 11 cases out of 13, 85% by the Japanese UTI criteria. Bacteriologically, 20 strains out of 22, 91% were eradicated after the therapy. Against strains of Pseudomonas aeruginosa, the response was 1 out of 3 strains. In the safety profile, no side events or abnormal laboratory findings were caused by FK037.
|Number of pages||6|
|Publication status||Published - 1994|
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Infectious Diseases
- Drug Discovery