Clinical study of NM441 on urinary tract infections

Keizo Suzuki; Masaki Horiba; Kiyohito Ishikawa; Yorio Naide; Kiyotaka Hoshinaga; Masanori Yanaoka; Shinobu Kato; Shinichi Ando; Norihiko Okishio; Haruyoshi Asano

Clinical study of NM441 on urinary tract infections

Keizo Suzuki, Masaki Horiba, Kiyohito Ishikawa, Yorio Naide, Kiyotaka Hoshinaga, Masanori Yanaoka, Shinobu Kato, Shinichi Ando, Norihiko Okishio, Haruyoshi Asano

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.

Original language	English
Pages (from-to)	678-683
Number of pages	6
Journal	Japanese Journal of Chemotherapy
Volume	44
Issue number	SUPPL. 1
Publication status	Published - 1996
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)

Cite this

@article{ac2e5b22677b4dfc93e3f6f6c70b1aca,

title = "Clinical study of NM441 on urinary tract infections",

abstract = "NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.",

author = "Keizo Suzuki and Masaki Horiba and Kiyohito Ishikawa and Yorio Naide and Kiyotaka Hoshinaga and Masanori Yanaoka and Shinobu Kato and Shinichi Ando and Norihiko Okishio and Haruyoshi Asano",

year = "1996",

language = "English",

volume = "44",

pages = "678--683",

journal = "Japanese Journal of Chemotherapy",

issn = "1340-7007",

publisher = "Japan Society of Chemotherapy",

number = "SUPPL. 1",

}

TY - JOUR

T1 - Clinical study of NM441 on urinary tract infections

AU - Suzuki, Keizo

AU - Horiba, Masaki

AU - Ishikawa, Kiyohito

AU - Naide, Yorio

AU - Hoshinaga, Kiyotaka

AU - Yanaoka, Masanori

AU - Kato, Shinobu

AU - Ando, Shinichi

AU - Okishio, Norihiko

AU - Asano, Haruyoshi

PY - 1996

Y1 - 1996

N2 - NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.

AB - NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.

UR - http://www.scopus.com/inward/record.url?scp=15844425967&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15844425967&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:15844425967

SN - 1340-7007

VL - 44

SP - 678

EP - 683

JO - Japanese Journal of Chemotherapy

JF - Japanese Journal of Chemotherapy

IS - SUPPL. 1

ER -

Clinical study of NM441 on urinary tract infections

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this