Clinical value of CA125, CA19-9, CEA, CA72-4, and TPA in borderline ovarian tumor

Koji Tamakoshi, Fumitaka Kikkawa, Kiyosumi Shibata, Kiyoshi Tomoda, Naoko H. Obata, Fumiyo Wakahara, Yahito Tokuhashi, Hisatake Ishikawa, Michiyasu Kawai, Yutaka Tomoda

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Five tumor markers were analyzed clinically in 101 patients with borderline ovarian tumors who were treated by the Tokai Ovarian Tumor Study Group, an association comprising Nagoya University and its affiliated hospital, between January 1986 and December 1994. The positive rate of CA125 was 68.2% in serous tumor and 51.9% in mucinous tumor. The positive rate of CA19-9 was 51.5% in serous tumor and 44.7% in mucinous tumor. The positive rates and mean serum levels of CA125 in serous and mucinous tumor by stage had rising tendencies with an increase in each stage. The mean serum levels of CA19-9 in serous and mucinous tumor by stage had rising tendencies with an increase in each stage. CA125 and CA19-9 were useful for screening of borderline ovarian tumors. The positive rates of CEA and TPA in mutinous tumor were 32.5 and 27.3%, respectively, although none of the patients with serous tumor were positive in CEA and TPA. The positive rates and mean serum levels of CEA in mucinous tumor by stage had rising tendencies with an increase in each stage. The positive rate of CA72-4 was significantly lower than that of CA125 (P < 0.05).

Original languageEnglish
Pages (from-to)67-72
Number of pages6
JournalGynecologic oncology
Volume62
Issue number1
DOIs
Publication statusPublished - 07-1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Fingerprint Dive into the research topics of 'Clinical value of CA125, CA19-9, CEA, CA72-4, and TPA in borderline ovarian tumor'. Together they form a unique fingerprint.

  • Cite this

    Tamakoshi, K., Kikkawa, F., Shibata, K., Tomoda, K., Obata, N. H., Wakahara, F., Tokuhashi, Y., Ishikawa, H., Kawai, M., & Tomoda, Y. (1996). Clinical value of CA125, CA19-9, CEA, CA72-4, and TPA in borderline ovarian tumor. Gynecologic oncology, 62(1), 67-72. https://doi.org/10.1006/gyno.1996.0191