Twenty-nine cases of mucinous carcinoma in the colorectum, except for multiple or fistulae cancer were clinicopathologically compared with 470 cases of well-and 162 cases of moderately-differentiated adenocarcinoma. The depth of invasion was se or more in 78.9% of mucinous carcinoma of colon, and all mucinous carcinoma of rectum invaded as a1. Node metastases up to the second grade were more often seen in mucinous carcinoma of the colon (44.4%) and the rectum (40.0%) than in the other histologic types. There was no significant difference in the incidence of distant metastasis and peritoneal dissemination between mucinous carcinoma and well-and moderately- differentiated adenocarcinoma. The five-year survival rate of mucinous carcinoma was 53.3% in the colon, and 64.9% in the rectum. Curative A resection rates were 77.8% in the colon, and 80.0% in the rectum. Curative resection was expected for mucinous carcinoma by wide resection and sufficient lymphadenectomy. There was no significant difference in the five- year survival rate between mucinous carcinoma and well-and moderately- differentiated adenocarcinoma. The adjuvant therapy for mucinous carcinoma with Dukes' C was recommended in the colon because the five-year survival rate of Dukes' C (37.5%) was worse in mucinous carcinoma of colon than in well-differentiated adenocarcinoma. More accurate method for diagnosis of mucinous carcinoma was needed because preoperative histological diagnosis was poor in the colon (45.0%) and the rectum (16.0%).
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