Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b

Mami Hata; Masahiro Suzuki; Masakado Matsumoto; Masao Takahashi; Katsuhiko Sato; Shiro Ibe; Kenji Sakae

doi:10.1128/AAC.49.2.801-803.2005

Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b

Mami Hata, Masahiro Suzuki, Masakado Matsumoto, Masao Takahashi, Katsuhiko Sato, Shiro Ibe, Kenji Sakae

Research output: Contribution to journal › Article › peer-review

262 Citations (Scopus)

Abstract

A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.

Original language	English
Pages (from-to)	801-803
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	49
Issue number	2
DOIs	https://doi.org/10.1128/AAC.49.2.801-803.2005
Publication status	Published - 02-2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.49.2.801-803.2005

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abstract = "A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.",

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AU - Hata, Mami

AU - Suzuki, Masahiro

AU - Matsumoto, Masakado

AU - Takahashi, Masao

AU - Sato, Katsuhiko

AU - Ibe, Shiro

AU - Sakae, Kenji

PY - 2005/2

Y1 - 2005/2

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AB - A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.

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ER -

Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b

Abstract

All Science Journal Classification (ASJC) codes

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