Cohort profile of the Japan collaborative cohort study at final follow-up

Akiko Tamakoshi, Kotaro Ozasa, Yoshihisa Fujino, Koji Suzuki, Kiyomi Sakata, Mitsuru Mori, Shogo Kikuchi, Hiroyasu Iso, Mitsuru Mori, Fumio Sakauchi, Yutaka Motohashi, Ichiro Tsuji, Yosikazu Nakamura, Haruo Mikami, Michiko Kurosawa, Yoshiharu Hoshiyama, Naohito Tanabe, Koji Tamakoshi, Kenji Wakai, Shinkan TokudomeShuji Hashimoto, Yasuhiko Wada, Takashi Kawamura, Yoshiyuki Watanabe, Tsuneharu Miki, Chigusa Date, Kiyomi Sakata, Yoichi Kurozawa, Takesumi Yoshimura, Akira Shibata, Naoyuki Okamoto, Hideo Shio

Research output: Contribution to journalArticlepeer-review

134 Citations (Scopus)


The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) was established in the late 1980s to evaluate the risk impact of lifestyle factors and levels of serum components on human health. During the 20-year follow-up period, the results of the study have been published in almost 200 original articles in peer-reviewed English-language journals. However, continued follow-up of the study subjects became difficult because of the retirements of principal researchers, city mergers throughout Japan in the year 2000, and reduced funding. Thus, we decided to terminate the JACC Study follow-up at the end of 2009. As a final point of interest, we reviewed the population registry information of survivors. A total of 207 (0.19%) subjects were ineligible, leaving 110 585 eligible participants (46 395 men and 64 190 women). Moreover, errors in coding date of birth and sex were found in 356 (0.32%) and 59 (0.05%) cases, respectively, during routine follow-up and final review. Although such errors were unexpected, their impact is believed to be negligible because of the small numbers relative to the large total study population. Here, we describe the final cohort profile at the end of the JACC Study along with selected characteristics of the participants and their status at the final follow-up. Although follow-up of the JACC Study participants is finished, we will continue to analyze and publish study results.

Original languageEnglish
Pages (from-to)227-232
Number of pages6
JournalJournal of epidemiology
Issue number3
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Epidemiology


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