Color-mapping of 4D-CTA for the detection of cranial arteriovenous shunts

M. Meijs, S. A.H. Pegge, K. Murayama, H. D. Boogaarts, M. Prokop, P. W.A. Willems, R. Manniesing, F. J.A. Meijer

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Abstract

BACKGROUND AND PURPOSE: 4D CT angiography is increasingly used in clinical practice for the assessment of different neurovascular disorders. Optimized processing of 4D-CTA is crucial for diagnostic interpretation because of the large amount of data that is generated. A color-mapping method for 4D-CTA is presented for improved and enhanced visualization of the cerebral vasculature hemodynamics. This method was applied to detect cranial AVFs. MATERIALS AND METHODS: All patients who underwent both 4D-CTA and DSA in our hospital from 2011 to 2018 for the clinical suspicion of a cranial AVF or carotid cavernous fistula were retrospectively collected. Temporal information in the cerebral vasculature was visualized using a patient-specific color scale. All color-maps were evaluated by 3 observers for the presence or absence of an AVF or carotid cavernous fistula. The presence or absence of cortical venous reflux was evaluated as a secondary outcome measure. RESULTS: In total, 31 patients were included, 21 patients with and 10 without an AVF. Arterialization of venous structures in AVFs was accurately visualized using color-mapping. There was high sensitivity (86%-100%) and moderate-to-high specificity (70%-100%) for the detection of AVFs on color-mapping 4D-CTA, even without the availability of dynamic subtraction rendering. The diagnostic performance of the 3 observers in the detection of cortical venous reflux was variable (sensitivity, 43%-88%; specificity, 60%-80%). CONCLUSIONS: Arterialization of venous structures can be visualized using color-mapping of 4D-CTA and proves to be accurate for the detection of cranial AVFs. This finding makes color-mapping a promising visualization technique for assessing temporal hemodynamics in 4D-CTA.

Original languageEnglish
Pages (from-to)1498-1504
Number of pages7
JournalAmerican Journal of Neuroradiology
Volume40
Issue number9
DOIs
Publication statusPublished - 01-01-2019

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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Meijs, M., Pegge, S. A. H., Murayama, K., Boogaarts, H. D., Prokop, M., Willems, P. W. A., Manniesing, R., & Meijer, F. J. A. (2019). Color-mapping of 4D-CTA for the detection of cranial arteriovenous shunts. American Journal of Neuroradiology, 40(9), 1498-1504. https://doi.org/10.3174/ajnr.A6156