Combined seminested polymerase chain reaction and heteroduplex analysis for detecting monoclonality of IgH rearrangement in patients with follicular lymphoma

Amaylia Oehadian, Naoki Koide, Mya Mya Mu, Ferdaus Hassan, Tomoaki Yoshida, Takashi Yokochi

Research output: Contribution to journalArticlepeer-review

Abstract

A new, sensitive method combining seminested polymerase chain reaction (PCR) and heteroduplex analysis was used to detect follicular lymphoma (FL) cells in peripheral blood. Based on the detection of IgH rearrangemen in DNA from peripheral blood leukocytes, the method demonstrated the presence of monoclonal B cells in FL patients with high frequency.

Original languageEnglish
Pages (from-to)1273-1275
Number of pages3
JournalHaematologica
Volume89
Issue number10
Publication statusPublished - 01-10-2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Hematology

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