TY - JOUR
T1 - Comparison Between the Internal and External Pressure Filtration Method of Cell-Free and Concentrated Ascites Reinfusion Therapy Using the Same Cancerous Ascites
AU - Yamada, Sachie
AU - Hasegawa, Midori
AU - Nii, Norio
AU - Kato, Masao
AU - Ohashi, Atsushi
AU - Suzuki, Ryota
AU - Komatsu, Masakazu
AU - Abe, Kosei
AU - Hata, Yosuke
AU - Takahashi, Kazuo
AU - Hayashi, Hiroki
AU - Koide, Shigehisa
AU - Tsuboi, Naotake
AU - Inaguma, Daijo
AU - Yuzawa, Yukio
N1 - Publisher Copyright:
© 2019 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy
PY - 2019/6
Y1 - 2019/6
N2 - Cell-free and concentrated ascites reinfusion therapy (CART) by internal filtration pressure method (internal method) and external filtration pressure method (external method) using the same cancerous ascites was performed. The rate of rise in circuit pressure and recovered components were compared between the two methods. The factors related to circuit pressure rise were also researched. In both methods, circuit pressure rose in 50% of cases. The recovery rates of IgG, IgA, IgM, and haptoglobin were significantly higher for the internal method than for the external method, whereas the recovery rate of α1-antitrypsin was significantly lower in the internal method than in the external method. The levels of IL-6, haptoglobin, α1-antitrypsin, and fibrinogen/fibrindegradation products (FDP) in the original ascites were significantly higher in the group wherein circuit pressure rose than in that without circuit pressure rise. These proteins might be related to the rise in circuit pressure.
AB - Cell-free and concentrated ascites reinfusion therapy (CART) by internal filtration pressure method (internal method) and external filtration pressure method (external method) using the same cancerous ascites was performed. The rate of rise in circuit pressure and recovered components were compared between the two methods. The factors related to circuit pressure rise were also researched. In both methods, circuit pressure rose in 50% of cases. The recovery rates of IgG, IgA, IgM, and haptoglobin were significantly higher for the internal method than for the external method, whereas the recovery rate of α1-antitrypsin was significantly lower in the internal method than in the external method. The levels of IL-6, haptoglobin, α1-antitrypsin, and fibrinogen/fibrindegradation products (FDP) in the original ascites were significantly higher in the group wherein circuit pressure rose than in that without circuit pressure rise. These proteins might be related to the rise in circuit pressure.
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U2 - 10.1111/1744-9987.12821
DO - 10.1111/1744-9987.12821
M3 - Article
C2 - 31025830
AN - SCOPUS:85067417327
SN - 1744-9979
VL - 23
SP - 237
EP - 241
JO - Therapeutic Apheresis and Dialysis
JF - Therapeutic Apheresis and Dialysis
IS - 3
ER -