Comparison of PCR for sputum samples obtained by induced cough and serological tests for diagnosis of Mycoplasma pneumoniae infection in children

Tsutomu Yamazaki, Mitsuo Narita, Nozomu Sasaki, Tsuyoshi Kenri, Yoshichika Arakawa, Tsuguo Sasaki

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Passive agglutination (PA) and immunoglobulin M (IgM), IgA, and IgG enzyme-linked immunosorbent assays (ELISAs) for the diagnosis of Mycoplasma pneumoniae were compared with PCR testing of sputum samples obtained from children with lower respiratory tract infections. The sensitivity and specificity of PA were 80.3% and 92.3% at a titer of 1:80. ELISA was found to be less sensitive than PA.

Original languageEnglish
Pages (from-to)708-710
Number of pages3
JournalClinical and Vaccine Immunology
Volume13
Issue number6
DOIs
Publication statusPublished - 06-2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry
  • Microbiology (medical)

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